CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1079
Family Name 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine receptor 1B Ligand GR-127935 Family
No. of Seeds 7 No. of Other Members 5
Family Centroid CFAMM00227086 Functional Category Investigative Drug
Superfamily 5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine receptor 1A Binder Superfamily
Class Class 1632

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
5-hydroxytryptamine receptor 1B Ligand Sb 224289 Family 2 8
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 3 8
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 7 4
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 0
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 3 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 6 2
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00227087 CHEMBL151420 Bioactive N-[4-(2-fluoroethoxy)-3-(4-methylpiperazin-1-yl)phenyl]-4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]benzamide
CFAMM00227094 CHEMBL21790 Bioactive N-[3-[3-(dimethylamino)propyl]-4-methoxyphenyl]-4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]benzamide
CFAMM00227082 CHEMBL20791 Bioactive N-[4-[2-(dimethylamino)ethyl]-2,3-dihydro-1,4-benzoxazin-6-yl]-4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]benzamide
CFAMM00227093 CHEMBL282693 Bioactive N-[3-[2-(dimethylamino)ethylamino]-4-methoxyphenyl]-4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]benzamide
CFAMM00227080 CHEMBL422504 Bioactive SureCN7801411
CFAMM00227086 DNC003505 Investigative Drug GR-127935

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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