CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1098
Family Name 5-hydroxytryptamine receptor 7 and D(2) dopamine receptor Ligand SB-258719 Family
No. of Seeds 3 No. of Other Members 29
Family Centroid CFAMM00227497 Functional Category Investigative Drug
Superfamily Acetylcholinesterase and D(2) dopamine receptor Binder Superfamily
Class Class 1974

Cousin Family NamesSeedsMembers
Potassium voltage-gated channel subfamily H member 2 Ligand 4-... 4 26
Alpha-2A adrenergic receptor Ligand SK&F-29661 Family 3 42
Acetylcholinesterase Inhibitor 1-benzene Sulfonyl-cis-2,6-dime... 1 4
D(2) dopamine receptor Ligand 4-[3-(methylsulfonyl)phenyl]-1-p... 2 2
Oxytocin receptor and Vasopressin V1a receptor Ligand 1'-tosyl... 1 7
Squalene synthase Inhibitor Zwitterionic Sulfobetaine Derivati... 2 20
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 6 7
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (1S,5... 2 4
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 34
5-hydroxytryptamine receptor 2A and Potassium voltage-gated ch... 2 11
C-C chemokine receptor type 5 ligand methyl N-[1-[(3S)-4-[benz... 3 18
Histamine H3 receptor ligand 2-[4-[4-[2-[(2R)-2-methylpyrrolid... 4 11
Histamine H3 receptor and Potassium voltage-gated channel subf... 6 3
Histamine H3 receptor and Potassium voltage-gated channel subf... 4 0
Histamine H3 receptor and Potassium voltage-gated channel subf... 14 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 10
Sigma non-opioid intracellular receptor 1 ligand 1-benzyl-4-[(... 3 2
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 6 7
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 4 0
C-C chemokine receptor type 5 ligand AC1L9YN4 family 2 33
Histamine H3 receptor and Potassium voltage-gated channel subf... 5 0
Histamine H3 receptor ligand N,N-diethyl-4-[4-[2-[(2R)-2-methy... 4 0
Neuropeptide Y receptor type 5 ligand AGN-PC-0A7RNK family 2 1
Sigma non-opioid intracellular receptor 1 ligand N-methyl-N-[(... 1 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00227496 CHEMBL94984 Bioactive SureCN3827869
CFAMM00227505 DNC003586 Investigative Drug SB-258741
CFAMM00227497 DNC003549 Investigative Drug SB-258719

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27759 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543