CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Aldose reductase Inhibitor Tingenone Family
No. of Seeds 2 No. of Other Members 9
Family Centroid CFAMM00173852 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Aldose reductase Binder Superfamily
Class Class 1356

Cousin Family NamesSeedsMembers
Aminopeptidase N Inhibitor [(125)i] RB129 Family 11 204
Glycogen phosphorylase, muscle form and Tyrosine-protein phosp... 4 12
DNA polymerase and Glycogen phosphorylase, muscle form Inhibit... 32 22
Aldose reductase Inhibitor Tingenin B Family 2 0
Glycogen phosphorylase, muscle form Inhibitor 2-hydroxyiminool... 8 13


External ID

Functional Category

Molecule Name

CFAMM00173852 DNC013881 Investigative Drug TINGENONE
CFAMM00173863 DPR000028 Investigative Drug Celastrol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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