CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1104
Family Name 5-hydroxytryptamine receptor 5A and 5-hydroxytryptamine receptor 6 Ligand Methiothepin Family
No. of Seeds 12 No. of Other Members 20
Family Centroid CFAMM00227798 Functional Category Investigative Drug
Superfamily Muscarinic acetylcholine receptor M5 Ligand Metixene Superfamily
Class Class 241

Cousin Family NamesSeedsMembers
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Muscarinic acetylcholine receptor M5 Ligand Metixene Family 5 24
Muscarinic acetylcholine receptor M3 Ligand Diphemanil Methyls... 22 45
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 2 39
Potassium voltage-gated channel subfamily H member 2 Ligand 4-... 4 26
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 4 4
Melanin-concentrating hormone receptor 1 Ligand 2-phenyl-n,n-b... 1 0
Melanin-concentrating hormone receptor 1 Ligand N,n-bis(tosylm... 2 1
Sodium-dependent dopamine transporter Inhibitor 1-(1-benzo[b]t... 5 5
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
5-hydroxytryptamine receptor 1A Ligand 2-(biphenyl-3-ylthio)-n... 1 3
Sodium-dependent serotonin transporter and Sodium-dependent no... 12 0
Alpha-1B adrenergic receptor and Alpha-1A adrenergic receptor ... 1 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 7 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 34
5-hydroxytryptamine receptor 2A and Potassium voltage-gated ch... 2 11
Sigma non-opioid intracellular receptor 1 and 3-beta-hydroxyst... 4 12
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 10
Sigma non-opioid intracellular receptor 1 ligand 1-benzyl-4-[(... 3 2
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 4 0
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 2 2
Squalene synthase inhibitor SureCN8712667 family 1 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 1 1
D(4) dopamine receptor and 5-hydroxytryptamine receptor 2A lig... 1 1
Ileal sodium/bile acid cotransporter inhibitor (3R,5R)-3-butyl... 1 2
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 0
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 0
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00227780 CHEMBL1259080 Bioactive AGN-PC-087UF1
CFAMM00227794 CHEMBL1259097 Bioactive AGN-PC-087UF2
CFAMM00227779 CHEMBL39900 Bioactive SPIPETHIANE
CFAMM00227785 CHEMBL1259062 Bioactive AGN-PC-087UEY
CFAMM00227773 CHEMBL428892 Bioactive AC1OEMXJ
CFAMM00227766 CHEMBL1259112 Bioactive AC1L1RUX
CFAMM00227784 CHEMBL1259063 Bioactive AGN-PC-087UEZ
CFAMM00227765 CHEMBL1259113 Bioactive AGN-PC-09M52G
CFAMM00227783 CHEMBL1259043 Bioactive AGN-PC-087U9F
CFAMM00227796 CHEMBL1256737 Bioactive Methiothepin mesylate
CFAMM00227771 CHEMBL1259079 Bioactive AGN-PC-087UF0
CFAMM00227798 DNC003558 Investigative Drug METHIOTHEPIN

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27070 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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