CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1106
Family Name Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 Inhibitor SC-58451 Family
No. of Seeds 11 No. of Other Members 80
Family Centroid CFAMM00228188 Functional Category Investigative Drug
Superfamily Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 Binder Superfamily 2
Class Class 1516

Cousin Family NamesSeedsMembers
Nuclear factor NF-kappa-B p100 subunit Inhibitor BAY11-7082 Fa... 2 17
Prostaglandin G/H synthase 2 Inhibitor Dup-697 Family 2 10
Cytochrome P450 11B1, mitochondrial Inhibitor 3-meso2-dde Family 2 14
Prothrombin Inhibitor 4-tert-butylbenzenesulfonic Acid Family 1 39
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor P-TOLU... 5 27
Presenilin-1 and Presenilin-2 Inhibitor 1-chloro-4-(1-phenyl-c... 5 13
Kinesin-like protein KIF11 Inhibitor 4'-(trifluoromethyl)-4-bi... 10 8
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 1,1-d... 1 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 1-phe... 6 23
Beta-ketoacyl-acyl carrier protein synthase III Inhibitor 2-to... 1 3
Prostaglandin G/H synthase 2 Inhibitor (e)-2-(4-(methylsulfony... 5 6
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 4 4
Prostaglandin G/H synthase 2 inhibitor SureCN8385166 family 4 2
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 2 0
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 0
Prostaglandin G/H synthase 2 inhibitor AGN-PC-075FEE family 4 2
Carbonic anhydrase 9 and Carbonic anhydrase 1 inhibitor 3-[2-(... 2 0
Carbonic anhydrase 1 and Carbonic anhydrase 13 inhibitor 2,3,5... 4 3
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 2
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 3 0
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 1
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 2 12
Rap guanine nucleotide exchange factor 4 inhibitor 1,3,5-trime... 1 0
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00228156 CHEMBL1083415 Bioactive AGN-PC-035TBY
CFAMM00228226 CHEMBL91118 Bioactive 1-(3-methylidene-2-phenylcyclobuten-1-yl)-4-methylsulfonylbenzene
CFAMM00228231 CHEMBL92443 Bioactive AGN-PC-023AX0
CFAMM00228166 CHEMBL89429 Bioactive SureCN213199
CFAMM00228180 CHEMBL329999 Bioactive SureCN8383616
CFAMM00228195 CHEMBL90447 Bioactive SureCN215233
CFAMM00228187 CHEMBL92102 Bioactive SureCN8384084
CFAMM00228193 CHEMBL127674 Bioactive SureCN8652481
CFAMM00228171 CHEMBL92107 Bioactive SureCN8385002
CFAMM00228244 DNC003789 Investigative Drug SC-57666
CFAMM00228188 DNC003564 Investigative Drug SC-58451

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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