CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1117
Family Name 5-hydroxytryptamine receptor 6 Ligand SB-357134 Family
No. of Seeds 13 No. of Other Members 2
Family Centroid CFAMM00228470 Functional Category Investigative Drug
Superfamily 5-hydroxytryptamine receptor 6 Ligand SB-357134 Superfamily
Class Class 1633

Cousin Family NamesSeedsMembers
Tumor necrosis factor Inhibitor Tgaac-94 Family 6 107
5-hydroxytryptamine receptor 6 Ligand Sb 258585 Family 11 121
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 20 33
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Pyruvate kinase PKLR and Pyruvate kinase PKM inhibitor AGN-PC-... 1 1
5-hydroxytryptamine receptor 6 ligand N-(3,5-dichlorophenyl)-4... 7 2
Alpha-2A adrenergic receptor and 5-hydroxytryptamine receptor ... 7 10
5-hydroxytryptamine receptor 6 ligand 1-(4-methoxy-3-piperazin... 6 3
5-hydroxytryptamine receptor 6 ligand 8-chloro-2-(4-methoxy-3-... 4 1
5-hydroxytryptamine receptor 6 ligand 6-bromo-1-(4-methoxy-3-p... 2 0
5-hydroxytryptamine receptor 6 ligand AGN-PC-0BRZ7B family 9 2
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 14
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 2 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 10 1
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 5 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 5 1
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 4-met... 3 3
5-hydroxytryptamine receptor 6 ligand N-(3-bromo-2,5-dichlorop... 2 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 1


External ID

Functional Category

Molecule Name

CFAMM00228474 CHEMBL155106 Bioactive N-(2-bromophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
CFAMM00228466 CHEMBL154367 Bioactive N-(3-bromophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
CFAMM00228465 CHEMBL356021 Bioactive 7-bromo-1-(4-methoxy-3-piperazin-1-ylphenyl)sulfonyl-3,4-dihydro-2H-quinoline
CFAMM00228480 CHEMBL348364 Bioactive N-(3,5-dibromo-2-fluorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
CFAMM00228472 CHEMBL154274 Bioactive N-(2,5-dibromophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
CFAMM00228464 CHEMBL155717 Bioactive N-(3,5-dibromophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
CFAMM00228479 CHEMBL350026 Bioactive N-(2-bromo-4-methylphenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
CFAMM00228469 CHEMBL154720 Bioactive N-(3,5-dibromo-2-chlorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
CFAMM00228477 CHEMBL154842 Bioactive N-(2-bromo-3,5-dichlorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
CFAMM00228476 CHEMBL153918 Bioactive N-(2,5-dibromo-3-chlorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
CFAMM00228475 CHEMBL154534 Bioactive N-(5-bromo-2-chloro-3-fluorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
CFAMM00228467 CHEMBL154641 Bioactive 4-methoxy-3-piperazin-1-yl-N-(2,3,5-tribromophenyl)benzenesulfonamide
CFAMM00228470 DNC003592 Investigative Drug SB-357134

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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