CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1121
Family Name Voltage-dependent T-type calcium channel subunit alpha-1I Ligand KYS-05056 Family
No. of Seeds 9 No. of Other Members 19
Family Centroid CFAMM00228516 Functional Category Investigative Drug
Superfamily Voltage-dependent T-type calcium channel subunit alpha-1I Ligand KYS-05056 Superfamily
Class Class 1455

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 43 161
5-hydroxytryptamine 2 receptor Ligand Ketanserin Family 10 253
Motilin receptor Ligand GSK962040 Family 30 457
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
B2 bradykinin receptor Ligand Quinapril Analogue Family 1 8
Cholecystokinin receptor type A Ligand L-708474 Family 14 82
Cannabinoid receptor 1 Ligand 1,3,5-triphenylimidazolidine-2,4... 2 17
Voltage-dependent T-type calcium channel subunit alpha-1I and ... 5 0
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Substance-P receptor ligand (2S)-2-N-[(2S)-1-[benzyl(methyl)am... 6 3
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 5 14
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 15 12
Furin inhibitor N-[(2S)-1-[[(2S)-1-[[(2S)-1-(4-carbamimidoylan... 3 16
Proteinase-activated receptor 1 ligand 2-[[2-[[2-[acetyl-[(E)-... 6 15
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 11 4
Tryptase alpha/beta-1 and Tryptase delta inhibitor SureCN75047... 4 2
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 2 5
Transient receptor potential cation channel subfamily V member... 1 1
P2X purinoceptor 7 inhibitor N-[1-[(Z)-[(cyanoamino)-(2-methyl... 1 2
Collagenase 3 and Interstitial collagenase inhibitor (2R,3S)-N... 1 0
P2X purinoceptor 7 inhibitor 2-(4-chlorophenyl)-N-[1-[(Z)-[(cy... 1 0
1,3,3,5-tetramethylspiro[indole-2,6'-piperidine]-2'-one NP 1,3... 2 0


External ID

Functional Category

Molecule Name

CFAMM00228515 DNC009230 Investigative Drug KYS-05055
CFAMM00228514 DNC004980 Investigative Drug KYS-05050
CFAMM00228488 DNC007910 Investigative Drug KYS-05080
CFAMM00228505 DNC003605 Investigative Drug KYS-05001
CFAMM00228513 DNC007829 Investigative Drug KYS-05090
CFAMM00228487 DNC007911 Investigative Drug KYS-05077
CFAMM00228521 DNC006877 Investigative Drug KYS-05074
CFAMM00228516 DNC009231 Investigative Drug KYS-05056
CFAMM00228507 DNC003608 Investigative Drug KYS-05040

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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