CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1129
Family Name Epidermal growth factor receptor Ligand 5,6-bis-p-tolylamino-isoindole-1,3-dione Family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00228641 Functional Category Investigative Drug
Superfamily Epidermal growth factor receptor Ligand 5,6-bis-p-tolylamino-isoindole-1,3-dione Superfamily
Class Class 1283

Cousin Family NamesSeedsMembers
5-alpha reductase inhibitor azasteroid derivative Dutasteride ... 36 124
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
Tumor necrosis factor Inhibitor Thalidomide Family 3 50
Serum albumin Inhibitor Ebselen Family 3 62
Motilin receptor Ligand GSK962040 Family 30 457
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
Pan-DAC Inhibitor AR-42 Family 21 153
Amonafide family 3 35
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Poly [ADP-ribose] polymerase 1 Inhibitor 8-amino-6h,11h-indeno... 3 9
Acetylcholinesterase Inhibitor Bw-28c51 Family 3 8
Telomerase reverse transcriptase Inhibitor 2,7-dinitroantraqui... 3 8
Oxysterols receptor LXR-alpha Ligand 2-(2-phenethylphenyl)isoi... 4 7
Transient receptor potential cation channel subfamily V member... 1 5
Cannabinoid receptor 2 Ligand N1-(4-bromophenyl)-n2,n2-dipenty... 4 21
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Telomerase reverse transcriptase Inhibitor 2,7-bis[2-(piperidi... 6 8
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
Histone deacetylase 2 Inhibitor N-(4-amino-4'-bromobiphenyl-3-... 1 1
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
5-hydroxytryptamine receptor 2A Ligand N-(1-(4-nitrobenzyl)pip... 4 6
Cholecystokinin receptor type A Ligand VL-0494 Family 1 0
Acetylcholinesterase inhibitor AGN-PC-07ZFTY family 1 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor [(2S)-2... 9 6
Acetylcholinesterase inhibitor 2-[2-(1-benzylpiperidin-4-yl)et... 2 9
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 2 4
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 4 3
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075BLN ... 2 1
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 5 19
Histone deacetylase 1 inhibitor SureCN3642893 family 10 23
Histone deacetylase 6 and Histone deacetylase 2 inhibitor 4-[[... 2 1
Phospholipase D1 and Phospholipase D2 inhibitor N-[(2S)-1-[4-(... 3 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00228641 DNC003625 Investigative Drug 5,6-Bis-p-tolylamino-isoindole-1,3-dione
CFAMM00228643 DNC003638 Investigative Drug CGP-53353

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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