CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1131
Family Name Integrin beta-3 Inhibitor FK-633 Family
No. of Seeds 2 No. of Other Members 12
Family Centroid CFAMM00228649 Functional Category Investigative Drug
Superfamily Plitidepsin Superfamily
Class Class 412

Cousin Family NamesSeedsMembers
Glycoprotein IIb/IIIa receptor Ligand Tirofiban Family 4 173
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Plasmepsin-1 and Plasmepsin-2 Inhibitor PS-777621 Family 11 13
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
Integrin beta-3 Inhibitor Lamifiban Family 3 4
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
Neprilysin and Angiotensin-converting enzyme inhibitor AGN-PC-... 3 7
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 6 1
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R)-7-[(4-ca... 3 14
Pol polyprotein inhibitor MDL 74538 family 11 1
Angiotensin-converting enzyme 2 and Neprilysin inhibitor (2S)-... 6 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2R)-3-[4-(2-me... 18 1
Tryptase alpha/beta-1 and Tryptase delta inhibitor (2S,3R)-4-o... 4 5
Cathepsin S and Cathepsin L1 inhibitor benzyl N-[(2S)-1-oxo-1-... 2 2
Pol polyprotein inhibitor (3S)-N-tert-butyl-2-[(2R)-2-[(3S,6S,... 3 1
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 1 0
Renin inhibitor (2S,4S,5S,7S)-5-amino-4-hydroxy-7-[[4-methoxy-... 2 0
Integrin beta-3 and Integrin alpha-IIb inhibitor FRADAFIBAN fa... 1 17
Stromelysin-1 inhibitor (2R)-2-[[(2S)-1-[(6S)-6-(methylcarbamo... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00228654 CHEMBL81056 Bioactive 2-[[(2R)-1-[(2S)-2-[2-(4-carbamimidoylphenoxy)ethyl]piperidin-1-yl]-3-cyclohexyl-1-oxopropan-2-yl]amino]acetic acid
CFAMM00228649 DNC003629 Investigative Drug FK-633

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27038 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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