CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1148
Family Name Oestrogen receptor and Estrogen receptor beta Ligand 2-(4-hydroxy-phenyl)-4-vinyl-quinolin-6-ol Family
No. of Seeds 10 No. of Other Members 17
Family Centroid CFAMM00229285 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Oestrogen receptor and Estrogen receptor beta Binder Superfamily 2
Class Class 1996

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Acetaminophen Family 2 42
D(2) dopamine receptor Ligand 2,3-dihydro-1h-indol-5-ol Family 1 4
High affinity nerve growth factor receptor and RAF proto-oncog... 3 29
Cannabinoid receptor 1 Ligand N-(4-methoxyphenyl)oleamide Family 4 23
Oestrogen receptor and Estrogen receptor beta Ligand 4-bromo-2... 3 0
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(... 7 18
Macrophage migration inhibitory factor Inhibitor 2-(4-hydroxys... 8 19
Indoleamine 2,3-dioxygenase 1 Inhibitor 4-(ethylamino)naphthal... 10 13
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 5 3
Amyloid beta A4 protein inhibitor SureCN6372684 family 2 7
NS3 inhibitor AGN-PC-074L2C family 1 3
Amino Acids and Derivatives Metabolite 5-Hydroxy-N-formylkynur... 3 3


External ID

Functional Category

Molecule Name

CFAMM00229286 DNC005834 Investigative Drug 2-(4-Hydroxy-phenyl)-4-methoxy-quinolin-6-ol
CFAMM00229292 DNC003666 Investigative Drug 2-(4-Hydroxy-phenyl)-quinolin-6-ol
CFAMM00229285 DNC005831 Investigative Drug 2-(4-Hydroxy-phenyl)-4-vinyl-quinolin-6-ol
CFAMM00229283 DNC005832 Investigative Drug 4-Ethyl-2-(4-hydroxy-phenyl)-quinolin-6-ol
CFAMM00229290 DNC007965 Investigative Drug 7-ethyl-6H-chromeno[4,3-b]quinoline-3,9-diol
CFAMM00229305 DNC005829 Investigative Drug 4-Chloro-2-(4-hydroxy-phenyl)-quinolin-6-ol
CFAMM00229282 DNC005833 Investigative Drug 4-Ethynyl-2-(4-hydroxy-phenyl)-quinolin-6-ol
CFAMM00229289 DNC007967 Investigative Drug 7-vinyl-6H-chromeno[4,3-b]quinoline-3,9-diol
CFAMM00229288 DNC007966 Investigative Drug 7-ethynyl-6H-chromeno[4,3-b]quinoline-3,9-diol
CFAMM00229287 DNC007969 Investigative Drug 7-chloro-6H-chromeno[4,3-b]quinoline-3,9-diol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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