CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1156
Family Name Mineralocorticoid receptor and Androgen receptor Ligand AL-43 Family
No. of Seeds 79 No. of Other Members 235
Family Centroid CFAMM00229622 Functional Category Investigative Drug with Natural Product
Superfamily Androgen receptor and Glucocorticoid receptor Binder Superfamily
Class Class 1999

Cousin Family NamesSeedsMembers
Potassium voltage-gated channel subfamily H member 2 Ligand Do... 5 30
Bcl-2 Inhibitor family 1 11
Dihydroorotate dehydrogenase and Interleukin-17A Inhibitor Vid... 4 74
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Peptidyl-prolyl cis-trans isomerase A Inhibitor 7-amino-4-meth... 4 59
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 11 20
Glucocorticoid receptor Ligand 1-methoxy-6-phenyl-6h-benzo[c]c... 9 16
Mineralocorticoid receptor and Androgen receptor Ligand LGD-55... 6 6
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 28
Acetylcholinesterase Inhibitor 6-methyl-4-(4-phenylpiperazin-1... 6 622
Progesterone receptor and Glucocorticoid receptor ligand AGN-P... 6 2
Progesterone receptor and Glucocorticoid receptor ligand (5Z)-... 2 1
Neuropeptide S receptor and Prelamin-A/C ligand CHEMBL1352632 ... 1 25
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 11 26
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 4 2
5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine recepto... 1 3
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... 15 0
Androgen receptor ligand 9-ethoxy-10-methoxy-4-methyl-1H-chrom... 3 4
Androgen receptor ligand trifluoromethyl 10-methoxy-4-methyl-2... 2 57
Androgen receptor ligand 10-(hydroxymethyl)-4-methyl-1,5-dihyd... 2 2
Androgen receptor ligand tert-butyl 4-methyl-2,5-dioxo-1H-chro... 3 0
Glucocorticoid receptor and Progesterone receptor ligand SureC... 2 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 11
Glucocorticoid receptor and Progesterone receptor ligand N-(1-... 1 1
Glucocorticoid receptor ligand N-[6-(3,4-dichlorophenyl)-1-met... 1 0
Progesterone receptor and Glucocorticoid receptor ligand (5Z)-... 2 2
Progesterone receptor and Androgen receptor ligand (4R,5S)-5-(... 5 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand Desac... 2 3
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00229431 CHEMBL267231 Bioactive SureCN4167709
CFAMM00229516 CHEMBL337112 Bioactive SureCN4172419
CFAMM00229650 CHEMBL62700 Bioactive (5Z)-5-(bromomethylidene)-9-fluoro-2,2,4-trimethyl-1H-chromeno[3,4-f]quinoline
CFAMM00229357 CHEMBL104037 Bioactive SureCN7954577
CFAMM00229370 CHEMBL65690 Bioactive (5Z)-9-fluoro-2,2,4-trimethyl-5-(3-methylbut-2-enylidene)-1H-chromeno[3,4-f]quinoline
CFAMM00229396 CHEMBL102403 Bioactive AGN-PC-0BPTEK
CFAMM00229643 CHEMBL453579 Bioactive (5S)-7,9-difluoro-2,2,4-trimethyl-5-[(1S)-3-methylcyclohex-2-en-1-yl]-1,5-dihydrochromeno[3,4-f]quinoline
CFAMM00229629 CHEMBL268239 Bioactive SureCN6294394
CFAMM00229437 CHEMBL320164 Bioactive AGN-PC-0BOOMN
CFAMM00229549 CHEMBL65014 Bioactive (5Z)-5-butylidene-9-fluoro-2,2,4-trimethyl-1H-chromeno[3,4-f]quinoline
CFAMM00229389 CHEMBL99123 Bioactive SureCN4172863
CFAMM00229575 CHEMBL101914 Bioactive AGN-PC-0BO38F
CFAMM00229649 CHEMBL140336 Bioactive SureCN4176522
CFAMM00229356 CHEMBL8639 Bioactive AGN-PC-0BHZK0
CFAMM00229388 CHEMBL134602 Bioactive (5Z)-5-benzylidene-9-fluoro-2,2,4-trimethyl-1H-chromeno[3,4-f]quinoline
CFAMM00229436 CHEMBL103237 Bioactive AGN-PC-0BR5WK
CFAMM00229521 CHEMBL141915 Bioactive SureCN4172432
CFAMM00229655 CHEMBL7671 Bioactive AGN-PC-07ZD2T
CFAMM00229621 CHEMBL8360 Bioactive 2,2,4-trimethyl-5-prop-2-enyl-10-prop-2-ynoxy-1,5-dihydrochromeno[3,4-f]quinoline
CFAMM00229401 CHEMBL132672 Bioactive (5Z)-9-fluoro-2,2,4-trimethyl-5-[(2-propan-2-ylphenyl)methylidene]-1H-chromeno[3,4-f]quinoline
CFAMM00229488 CHEMBL138098 Bioactive 10-methoxy-2,2,4-trimethyl-5-prop-2-ynyl-1,5-dihydrochromeno[3,4-f]quinoline
CFAMM00229561 CHEMBL335996 Bioactive (5Z)-9-fluoro-5-[(2-methoxyphenyl)methylidene]-2,2,4-trimethyl-1H-chromeno[3,4-f]quinoline
CFAMM00229587 CHEMBL137103 Bioactive SureCN4183653
CFAMM00229648 CHEMBL136464 Bioactive SureCN4179782
CFAMM00229661 CHEMBL97206 Bioactive SureCN4182659
CFAMM00229442 CHEMBL298687 Bioactive (5S)-10-methoxy-2,2,4-trimethyl-5-[(1S)-3-methylcyclohex-2-en-1-yl]-1,5-dihydrochromeno[3,4-f]quinoline
CFAMM00229394 CHEMBL330638 Bioactive SureCN4175513
CFAMM00229494 CHEMBL320423 Bioactive AGN-PC-0BN4DB
CFAMM00229641 CHEMBL413309 Bioactive (5Z)-5-benzylidene-7-fluoro-2,2,4-trimethyl-1H-chromeno[3,4-f]quinoline
CFAMM00229348 CHEMBL34882 Bioactive SureCN6650568
CFAMM00229407 CHEMBL1090805 Bioactive (5S)-10-ethynyl-2,2,4-trimethyl-5-prop-2-enyl-1,5-dihydrochromeno[3,4-f]quinoline
CFAMM00229421 CHEMBL7655 Bioactive SureCN4183846
CFAMM00229520 CHEMBL114941 Bioactive AGN-PC-074YU8
CFAMM00229593 CHEMBL7988 Bioactive SureCN4182727
CFAMM00229387 CHEMBL65079 Bioactive SureCN6649865
CFAMM00229547 CHEMBL318513 Bioactive SureCN6650300
CFAMM00229560 CHEMBL137982 Bioactive SureCN4174096
CFAMM00229620 CHEMBL113098 Bioactive AGN-PC-074YUL
CFAMM00229660 CHEMBL48588 Bioactive AGN-PC-073Q8B
CFAMM00229500 CHEMBL326092 Bioactive AGN-PC-074YUC
CFAMM00229599 CHEMBL320632 Bioactive AGN-PC-0BNBL0
CFAMM00229613 CHEMBL64294 Bioactive AGN-PC-074DMW
CFAMM00229393 CHEMBL133483 Bioactive (5Z)-9-fluoro-2,2,4-trimethyl-5-[(2-propylphenyl)methylidene]-1H-chromeno[3,4-f]quinoline
CFAMM00229480 CHEMBL335249 Bioactive (5Z)-9-fluoro-5-[(2-fluorophenyl)methylidene]-2,2,4-trimethyl-1H-chromeno[3,4-f]quinoline
CFAMM00229553 CHEMBL64913 Bioactive 9-fluoro-2,2,4-trimethyl-5-methylidene-1H-chromeno[3,4-f]quinoline
CFAMM00229653 CHEMBL141524 Bioactive SureCN4177478
CFAMM00229360 CHEMBL267940 Bioactive SureCN6291159
CFAMM00229506 CHEMBL103092 Bioactive AGN-PC-0BOKW1
CFAMM00229460 CHEMBL8209 Bioactive SureCN6291153
CFAMM00229619 CHEMBL104451 Bioactive AGN-PC-0BR310
CFAMM00229379 CHEMBL510305 Bioactive (5S)-5-[(1S)-cyclohex-2-en-1-yl]-7,9-difluoro-2,2,4-trimethyl-1,5-dihydrochromeno[3,4-f]quinoline
CFAMM00229499 CHEMBL115174 Bioactive AGN-PC-074YNK
CFAMM00229598 CHEMBL440454 Bioactive SureCN6294509
CFAMM00229466 CHEMBL507701 Bioactive (5S)-7,9-difluoro-2,2,4-trimethyl-5-[(1S,2R,6R)-6-methyl-7-oxabicyclo[4.1.0]heptan-2-yl]-1,5-dihydrochromeno[3,4-f]quinoline
CFAMM00229639 CHEMBL141282 Bioactive SureCN4183081
CFAMM00229652 CHEMBL336736 Bioactive SureCN4183619
CFAMM00229419 CHEMBL343135 Bioactive SureCN4182183
CFAMM00229492 CHEMBL116007 Bioactive AGN-PC-074YR4
CFAMM00229565 CHEMBL325221 Bioactive SureCN8806499
CFAMM00229578 CHEMBL336041 Bioactive SureCN4175015
CFAMM00229558 CHEMBL342426 Bioactive SureCN4169518
CFAMM00229571 CHEMBL415524 Bioactive (5Z)-5-[(2-ethylphenyl)methylidene]-9-fluoro-2,2,4-trimethyl-1H-chromeno[3,4-f]quinoline
CFAMM00229618 CHEMBL418990 Bioactive AGN-PC-0BQTEP
CFAMM00229631 CHEMBL62981 Bioactive (5Z)-5-butan-2-ylidene-9-fluoro-2,2,4-trimethyl-1H-chromeno[3,4-f]quinoline
CFAMM00229645 CHEMBL510373 Bioactive (5S)-7,9-difluoro-2,2,4-trimethyl-5-[(1R)-3-methylcyclohex-2-en-1-yl]-1,5-dihydrochromeno[3,4-f]quinoline
CFAMM00229426 CHEMBL332264 Bioactive AGN-PC-074YR5
CFAMM00229584 CHEMBL134421 Bioactive SureCN4186176
CFAMM00229404 CHEMBL132578 Bioactive (5Z)-9-fluoro-2,2,4-trimethyl-5-[[2-(trifluoromethoxy)phenyl]methylidene]-1H-chromeno[3,4-f]quinoline
CFAMM00229478 CHEMBL114607 Bioactive SureCN8808541
CFAMM00229358 CHEMBL137890 Bioactive 10-methoxy-2,2,4-trimethyl-5-[(E)-prop-1-enyl]-1,5-dihydrochromeno[3,4-f]quinoline
CFAMM00229345 CHEMBL322108 Bioactive AGN-PC-074YTX
CFAMM00229384 CHEMBL138283 Bioactive AGN-PC-0BRKFV
CFAMM00229397 CHEMBL99046 Bioactive SureCN4171493
CFAMM00229530 CHEMBL337856 Bioactive (5Z)-7-fluoro-2,2,4-trimethyl-5-[(2-methylphenyl)methylidene]-1H-chromeno[3,4-f]quinoline
CFAMM00229351 CHEMBL32812 Bioactive SureCN4180167
CFAMM00229557 CHEMBL323324 Bioactive AGN-PC-0BI63Q
CFAMM00229537 CHEMBL435822 Bioactive SureCN4172902
CFAMM00229622 DNC003681 Investigative Drug AL-43
CFAMM00229355 DNC004217 Investigative Drug LG-120838

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27074 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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