CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1158
Family Name cAMP-dependent protein kinase type II-beta regulatory subunit and Protein kinase C eta type Inhibitor Balanol Family
No. of Seeds 34 No. of Other Members 81
Family Centroid CFAMM00229773 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily cAMP-dependent protein kinase type II-beta regulatory subunit and Protein kinase C eta type Inhibitor Balanol Superfamily
Class Class 2001

Cousin Family NamesSeedsMembers
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor Mycophenola... 4 353
C-C chemokine receptor type 5 Ligand GW873140 Family 6 78
Integrin alpha-4 Inhibitor Firategrast Family 3 93
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Leukotriene B4 receptor 1 Ligand SC-51146 Family 6 315
Protein farnesyltransferase subunit beta Inhibitor Cylindrol A... 3 43
Solute carrier family 22 member 6 Inhibitor 3r14s-ochratoxin A... 1 3
Peroxisome proliferator-activated receptor gamma ligand (9aS)-... 4 44
Estrogen receptor ligand 2-(3-hydroxy-6-oxoxanthen-9-yl)-5-[[4... 1 2
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 14 1
Pol polyprotein inhibitor AC1LA3AI family 5 9
Protein kinase C beta type and Protein kinase C eta type inhib... 1 0
Protein kinase C eta type and Protein kinase C delta type inhi... 1 4
C-C chemokine receptor type 3 ligand N-[(3R)-1-[(6-fluoronapht... 1 4
Protein kinase C beta type and Protein kinase C alpha type inh... 3 1
Inosine-5'-monophosphate dehydrogenase 2 inhibitor (E)-6-(4-hy... 1 10
Inosine-5'-monophosphate dehydrogenase 2 and Inosine-5'-monoph... 1 14
Putative NP ZINC02124510 Family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00229726 CHEMBL70078 Bioactive 2-[2,6-dihydroxy-4-[(3S,4R)-3-[(4-hydroxybenzoyl)amino]oxepan-4-yl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid
CFAMM00229739 CHEMBL1794808 Bioactive 2-[2,6-dihydroxy-4-[(1R,2S,4R)-4-hydroxy-2-[(4-hydroxybenzoyl)amino]cyclopentyl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid;2-[2,6-dihydroxy-4-[(1R,2S,4S)-4-hydroxy-2-[(4-hydroxybenzoyl)amino]cyclopentyl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid
CFAMM00229752 CHEMBL306373 Bioactive 2-[2,6-dihydroxy-4-[(3R,4R)-3-[(4-hydroxybenzoyl)amino]oxepan-4-yl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid
CFAMM00229745 CHEMBL265559 Bioactive SureCN14129806
CFAMM00229712 CHEMBL422056 Bioactive 2-[2,6-dihydroxy-4-[(3S)-4-[(4-hydroxybenzoyl)amino]pyrrolidin-3-yl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid
CFAMM00229772 CHEMBL427118 Bioactive 2-[2,6-dihydroxy-4-[(2R)-2-[(4-hydroxybenzoyl)amino]cyclopentyl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid
CFAMM00229786 CHEMBL300422 Bioactive 2-[2,6-dihydroxy-4-[4-[(4-hydroxyphenyl)methyl]pyrrolidin-3-yl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid
CFAMM00229704 CHEMBL76920 Bioactive 2-[2,6-dihydroxy-4-[(1R,2R)-2-[(4-hydroxybenzoyl)amino]-4-propan-2-ylcyclopentyl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid
CFAMM00229751 CHEMBL304175 Bioactive Balanol Benzophenone Ester Analog 20
CFAMM00229765 CHEMBL177308 Bioactive 2-[2,6-dihydroxy-4-[[(1R)-1-[(4-hydroxybenzoyl)amino]-2,3-dihydro-1H-inden-2-yl]oxycarbonyl]benzoyl]-3-hydroxybenzoic acid
CFAMM00229778 CHEMBL306427 Bioactive 2-[2,6-dihydroxy-4-[(1R,2S,4S)-2-[(4-hydroxybenzoyl)amino]-4-(hydroxymethyl)cyclopentyl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid
CFAMM00229744 CHEMBL308263 Bioactive 2-[4-[(1R,2R,4R)-4-(aminomethyl)-2-[(4-hydroxybenzoyl)amino]cyclopentyl]oxycarbonyl-2,6-dihydroxybenzoyl]-3-hydroxybenzoic acid
CFAMM00229771 CHEMBL421866 Bioactive 2-[4-[(1R,2S,4S)-4-(aminomethyl)-2-[(4-hydroxybenzoyl)amino]cyclopentyl]oxycarbonyl-2,6-dihydroxybenzoyl]-3-hydroxybenzoic acid
CFAMM00229697 CHEMBL309034 Bioactive 2-[2,6-dihydroxy-4-[(1R,2R,4R)-4-hydroxy-2-[(4-hydroxybenzoyl)amino]cyclopentyl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid
CFAMM00229737 CHEMBL365598 Bioactive 4",6"-Dideoxybalanol, 6
CFAMM00229756 CHEMBL66923 Bioactive [(1R,2R)-2-[(4-hydroxybenzoyl)amino]cyclopentyl] 3,5-dihydroxy-4-(2-hydroxy-6-methoxycarbonylbenzoyl)benzoate
CFAMM00229797 CHEMBL71331 Bioactive 2-[2,6-dihydroxy-4-[(1S)-2-[(4-hydroxybenzoyl)amino]cyclopentyl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid
CFAMM00229710 CHEMBL48636 Bioactive Balanol Analog 41
CFAMM00229723 CHEMBL59828 Bioactive Balanol analog 4
CFAMM00229770 CHEMBL417051 Bioactive 2-[4-[(1R,2S,4R)-4-amino-2-[(4-hydroxybenzoyl)amino]cyclopentyl]oxycarbonyl-2,6-dihydroxybenzoyl]-3-hydroxybenzoic acid
CFAMM00229736 CHEMBL67290 Bioactive 2-[4-[(1R,2S,4R)-4-(aminomethyl)-2-[(4-hydroxybenzoyl)amino]cyclopentyl]oxycarbonyl-2,6-dihydroxybenzoyl]-3-hydroxybenzoic acid
CFAMM00229702 CHEMBL432168 Bioactive 2-[4-[(1R,2R,4R)-4-amino-2-[(4-hydroxybenzoyl)amino]cyclopentyl]oxycarbonyl-2,6-dihydroxybenzoyl]-3-hydroxybenzoic acid
CFAMM00229790 CHEMBL311399 Bioactive 2-[2,6-dihydroxy-4-[(3R)-3-[(4-hydroxybenzoyl)amino]azepan-4-yl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid
CFAMM00229803 CHEMBL177635 Bioactive 2-[2,6-dihydroxy-4-[(4R)-4-[(4-hydroxybenzoyl)amino]pyrrolidin-3-yl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid
CFAMM00229796 CHEMBL193697 Bioactive AC1NS3GT
CFAMM00229775 CHEMBL49354 Bioactive 2-{2,6-dihydroxy-4-[({3-[(4-hydroxybenzoyl)amino]azepan-4-yl}oxy)carbonyl]benzoyl}-3-hydroxybenzoic acid
CFAMM00229768 CHEMBL262980 Bioactive 2-[2,6-dihydroxy-4-[(1R,2R)-2-[(4-hydroxybenzoyl)amino]-4-(2,2,2-trifluoroacetyl)cyclopentyl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid
CFAMM00229795 CHEMBL306580 Bioactive 2-[2,6-dihydroxy-4-[(1R,2R)-4-hydroxy-2-[(4-hydroxybenzoyl)amino]cyclopentyl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid
CFAMM00229734 CHEMBL75661 Bioactive 2-[2,6-dihydroxy-4-[(1R,2R,4S)-2-[(4-hydroxybenzoyl)amino]-4-(hydroxymethyl)cyclopentyl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid
CFAMM00229714 CHEMBL307708 Bioactive 2-[4-[(1R,2R,4S)-4-(aminomethyl)-2-[(4-hydroxybenzoyl)amino]cyclopentyl]oxycarbonyl-2,6-dihydroxybenzoyl]-3-hydroxybenzoic acid
CFAMM00229794 CHEMBL67716 Bioactive 2-[2,6-dihydroxy-4-[(1R,2S,4S)-4-hydroxy-2-[(4-hydroxybenzoyl)amino]cyclopentyl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid
CFAMM00229746 CHEMBL59677 Bioactive 2-[2,6-dihydroxy-4-[[(3R,4R)-4-[(4-hydroxybenzoyl)amino]pyrrolidin-3-yl]carbamoyl]benzoyl]-3-hydroxybenzoic acid
CFAMM00229787 CHEMBL52529 Bioactive Balanol analog 5
CFAMM00229773 DNC003686 Investigative Drug BALANOL

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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