CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1166
Family Name Acetylcholinesterase Inhibitor Velnacrine Family
No. of Seeds 2 No. of Other Members 29
Family Centroid CFAMM00230136 Functional Category Investigative Drug with Natural Product
Superfamily Metabotropic glutamate receptor 5 and Acetylcholinesterase Binder Superfamily
Class Class 183

Cousin Family NamesSeedsMembers
Histamine N-methyltransferase inhibitor aminoquinoline Amodiaq... 8 23
Phospholipase A2 Inhibitor Quinacrine Family 13 95
Food vacuoles Inhibitor Mefloquine Family 2 25
Citric Acid family 2 58
Arachidonate 5-lipoxygenase-activating protein Inhibitor DG031... 3 206
Cytochrome b Inhibitor 2-nonyl-4-hydroxyquinoline N-OXIDE Family 2 22
Oestrogen receptor and Estrogen receptor beta Ligand ZK-119010... 2 16
Oestrogen receptor and Estrogen receptor beta Ligand 4-(3-phen... 5 14
Indoleamine 2,3-dioxygenase 1 Inhibitor 5-aminoquinolin-8-ol F... 3 16
DNA topoisomerase 1 Inhibitor 3-(4-phenyl-2,4'-bipyridin-6-yl)... 4 13
D(1B) dopamine receptor and D(2) dopamine receptor Ligand Flut... 1 6
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 38 35
Androgen receptor Ligand 11-methyl-6,11-dihydro-5h-benzo[a]car... 7 9
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(2-methyl... 7 27
Metabotropic glutamate receptor 5 Ligand 3-hydroxy-5-(2-methyl... 2 1
Metabotropic glutamate receptor 5 Ligand (3-(2-methylquinolin-... 3 6
Metabotropic glutamate receptor 5 Ligand 2-phenylethynyl-5,6,7... 1 4
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-09Q7W... 7 3
Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ... 5 8
Estrogen receptor beta and Estrogen receptor ligand 2-fluoro-4... 1 0
5-hydroxytryptamine receptor 2A ligand (3R,4R)-3-(2-phenyl-1H-... 1 18
Steroid hormone receptor ERR1 and Steroid hormone receptor ERR... 1 4
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 1
Inhibitor of nuclear factor kappa-B kinase subunit beta inhibi... 2 8
DNA topoisomerase 2-alpha and DNA topoisomerase 2-beta inhibit... 2 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00230136 DNC003711 Investigative Drug VELNACRINE
CFAMM00230113 DNC012794 Investigative Drug 9-Amino-1,2,3,4-tetrahydro-acridine-1,7-diol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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