CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1168
Family Name 5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine receptor 2B Ligand VER-5384 Family
No. of Seeds 11 No. of Other Members 20
Family Centroid CFAMM00230168 Functional Category Investigative Drug
Superfamily 5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine receptor 2B Ligand VER-5384 Superfamily
Class Class 1484

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand quinolone derivative Carteolol... 1 38
Potassium voltage-gated channel subfamily H member 2 Ligand Do... 5 30
D(2) dopamine receptor Ligand Aplindore Fumarate Family 2 30
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
Mineralocorticoid receptor and Androgen receptor Ligand AL-43 ... 79 235
Bifunctional epoxide hydrolase 2 Inhibitor 1-adamantan-1-yl-3-... 12 44
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 28
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 49 8
Survival motor neuron protein and DNA-(apurinic or apyrimidini... 1 5
Acetylcholinesterase inhibitor trimethyl-(2-methyl-3-propanoyl... 3 2
Acetylcholinesterase inhibitor AGN-PC-075N8G family 2 9
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 3 1
Gastrin/cholecystokinin type B receptor ligand 1-[3-[[2-(3-met... 2 12
Gonadotropin-releasing hormone receptor ligand SureCN5756131 f... 5 7
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 1
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 2 4
Histamine H3 receptor ligand N-[[2-[2-[(2R)-2-methylpyrrolidin... 4 1
Histamine H3 receptor ligand 3-[[2-[2-[(2R)-2-methylpyrrolidin... 3 1
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 4 19
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor [4-(2,... 2 11
Butyrylcholinesterase and Acetylcholinesterase inhibitor methy... 1 1
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 11
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 4 4
Neuropeptide Y receptor type 5 ligand 1-[1-(4-fluorophenyl)pro... 2 8
P2X purinoceptor 7 inhibitor 2-(1-adamantyl)-N-(3-methoxy-2-me... 2 4
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand Desac... 2 3
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-[2-... 1 0
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 0
Neuropeptide Y receptor type 1 ligand 1-(1-benzofuran-6-yl)-3-... 1 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00230154 CHEMBL344449 Bioactive SureCN6580903
CFAMM00230159 CHEMBL136431 Bioactive SureCN6580126
CFAMM00230165 CHEMBL138012 Bioactive SureCN6582669
CFAMM00230172 CHEMBL336268 Bioactive SureCN6582325
CFAMM00230178 CHEMBL136564 Bioactive SureCN6584601
CFAMM00230163 CHEMBL343825 Bioactive SureCN6580685
CFAMM00230177 CHEMBL136895 Bioactive SureCN6583137
CFAMM00230162 CHEMBL136531 Bioactive SureCN6584731
CFAMM00230155 CHEMBL342393 Bioactive SureCN6582423
CFAMM00230161 CHEMBL138744 Bioactive SureCN6582657
CFAMM00230168 DNC003716 Investigative Drug VER-5384

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27263 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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