CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1169
Family Name Potassium voltage-gated channel subfamily A member 3 Ligand CP-339818 Family
No. of Seeds 4 No. of Other Members 26
Family Centroid CFAMM00230184 Functional Category Investigative Drug with Human Metabolite
Superfamily 5-hydroxytryptamine receptor 6 and Potassium voltage-gated channel subfamily A member 3 Binder Superfamily
Class Class 22

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Noradrenergic re-uptake inhibitor Dibenzazepine Imipramine Family 8 178
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Serotonin re-uptake inhibitor Dibenzazepine Clomipramine Family 2 23
Calmodulin Inhibitor Aprindine Family 1 4
D(2) dopamine receptor Ligand Nomifensine Family 6 100
5-hydroxytryptamine receptor 6 Ligand 4-(1h-inden-1-ylmethyl)-... 5 99
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Progesterone receptor Ligand 2,2,4-trimethyl-6-phenyl-1,2-dihy... 5 82
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 67
5-hydroxytryptamine receptor 6 Ligand [2-(3h-indol-1-yl)-ethyl... 2 7
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 8 32
Acetylcholinesterase Inhibitor Bw-28c51 Family 3 8
Aromatase Inhibitor 3-amino-4'-amino-trans-stilbene Family 5 47
Kinesin-like protein KIF11 Inhibitor N-[4'-(trifluoromethyl)-4... 2 9
Dipeptidyl peptidase 4 Inhibitor (3s,4r)-3-butyl-1-phenylpiper... 2 40
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 47
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 42
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 18
5-hydroxytryptamine receptor 2A ligand AGN-PC-075LXD family 4 4
Prelamin-A/C and Alpha-2A adrenergic receptor ligand AMITRAZ f... 1 5
Sigma non-opioid intracellular receptor 1 ligand 1-[4-[1-adama... 4 23
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-[[4... 7 11
Carbonic anhydrase 2 inhibitor 1-(dimethylamino)-4-[(Z)-C-meth... 1 0
Epidermal growth factor receptor and Receptor tyrosine-protein... 2 9
D(4) dopamine receptor ligand 2-[4-[(3E)-3-ethoxyimino-3-pheny... 1 0
Nitric oxide synthase, brain and Nitric oxide synthase, induci... 1 1
Potassium voltage-gated channel subfamily A member 3 ligand AG... 1 8
Cholinesterase inhibitor 10-[[(1R,9aR)-2,3,4,6,7,8,9,9a-octahy... 1 0
Acetylcholinesterase inhibitor AGN-PC-075H4L family 1 0


External ID

Functional Category

Molecule Name

CFAMM00230188 CHEMBL1790020 Bioactive AGN-PC-0BFTEG
CFAMM00230210 DNC003931 Investigative Drug [1-Benzyl-1H-quinolin-(4E)-ylidene]-hexyl-amine
CFAMM00230184 DNC003721 Investigative Drug CP-339818
CFAMM00230205 DNC011312 Investigative Drug NSC-306843

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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