CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name D(2) dopamine receptor and D(1A) dopamine receptor Ligand A-70108 Family
No. of Seeds 16 No. of Other Members 27
Family Centroid CFAMM00181655 Functional Category Investigative Drug
Superfamily D(2) dopamine receptor and D(1A) dopamine receptor Ligand A-70108 Superfamily
Class Class 1347

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand catecholamine Dopamine family 9 170
Beta adrenergic receptor ligand catecholamine group Isoprotere... 7 130
Dopamine receptor ligand L-Tyrosine derivative Levodopa Family 4 59
Alpha adrenergic receptor ligand catecholamine Phenylephrine F... 4 39
Alpha-2 adrenergic receptor Ligand Oxymetazoline Family 5 4
Beta-2 adrenergic receptor ligand catecholamine Orciprenaline ... 13 13
Beta-2 adrenergic receptor ligand catecholamine Salbutamol Family 10 90
D(1A) dopamine receptor Ligand Fenoldopam Family 4 78
D(1B) dopamine receptor Ligand Apomorphine Family 30 271
Muscarinic acetylcholine receptor M3 Ligand Tolterodine Family 8 171
Alpha adrenergic receptor Ligand Bevantolol Family 4 48
Kappa-type opioid receptor Ligand Dezocine Family 36 46
5-hydroxytryptamine receptor 2A Ligand 3-methoxy-9-aminomethyl... 7 14
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 7 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 12
D(1A) dopamine receptor ligand DOXANTHINE family 3 0
D(1A) dopamine receptor and D(3) dopamine receptor ligand N,N-... 3 1
D(2) dopamine receptor and D(1A) dopamine receptor ligand (2R,... 3 2
Muscarinic acetylcholine receptor M3 and Beta-2 adrenergic rec... 2 1
D(1A) dopamine receptor and Adenylate cyclase type 5 ligand (1... 1 1


External ID

Functional Category

Molecule Name

CFAMM00181632 CHEMBL315005 Bioactive (1R)-1-(aminomethyl)-3-(3-methoxyphenyl)-3,4-dihydro-1H-isochromene-5,6-diol
CFAMM00181651 CHEMBL291143 Bioactive CHEBI:64080
CFAMM00181623 CHEMBL85689 Bioactive (1R)-1-(aminomethyl)-3-cyclooctyl-3,4-dihydro-1H-isochromene-5,6-diol
CFAMM00181629 CHEMBL313530 Bioactive AC1L21MN
CFAMM00181627 CHEMBL314459 Bioactive (1R)-1-(aminomethyl)-3-cyclohexyl-3,4-dihydro-1H-isochromene-5,6-diol
CFAMM00181641 CHEMBL85409 Bioactive (1R)-1-(aminomethyl)-3-(cyclopentylmethyl)-3,4-dihydro-1H-isochromene-5,6-diol
CFAMM00181626 CHEMBL313304 Bioactive (1R)-1-(aminomethyl)-3-(4-iodophenyl)-3,4-dihydro-1H-isochromene-5,6-diol
CFAMM00181645 DNC000118 Investigative Drug A 77636
CFAMM00181656 DNC012367 Investigative Drug 1-Aminomethyl-3-cyclohexyl-isochroman-5,6-diol
CFAMM00181655 DNC012366 Investigative Drug A-70108
CFAMM00181635 DNC012637 Investigative Drug 1-Aminomethyl-3-phenyl-isochroman-5,6-diol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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