CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1174
Family Name Thromboxane-A synthase Inhibitor CGS-13080 Family
No. of Seeds 3 No. of Other Members 19
Family Centroid CFAMM00230444 Functional Category Investigative Drug with Human Metabolite
Superfamily Thromboxane-A synthase Inhibitor CGS-13080 Superfamily
Class Class 1333

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
Metabotropic glutamate receptor 5 Ligand ADX-48621 Family 15 444
Telomerase protein component 1 Inhibitor GRN163L Family 5 29
Vascular endothelial growth factor Inhibitor PTC299 Family 6 145
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor CI-9... 3 13
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-cyanobenzyl... 14 13
Metabotropic glutamate receptor 5 Ligand 3-(4-pyridin-2-yl-imi... 6 5
cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor 6-im... 2 30
Farnesyl pyrophosphate synthase Inhibitor [2-(benzoimidazol-1-... 2 16
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-bromobenzyl... 3 0
Histamine H3 receptor Ligand 4-(2-(phenylamino)ethyl)-1h-imida... 5 16
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 4
Thromboxane-A synthase inhibitor AGN-PC-00N7V2 family 3 6
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 7 4
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 44
Carboxypeptidase B2 and Carboxypeptidase B inhibitor 3-(6-amin... 5 10
Nuclear receptor ROR-gamma and Mitogen-activated protein kinas... 1 10
Cytochrome P450 26A1 and Cytochrome P450 3A4 inhibitor AGN-PC-... 5 17
Adenosine deaminase inhibitor AGN-PC-00FYYU family 4 5
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 11 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 0
Thromboxane-A synthase and Thromboxane A2 receptor ligand Fce ... 12 20


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00230431 CHEMBL45685 Bioactive AGN-PC-00LGAR
CFAMM00230451 CHEMBL294924 Bioactive SureCN10982493
CFAMM00230444 DNC003737 Investigative Drug CGS-13080

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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