CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1186
Family Name Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 Inhibitor Tebufelone Family
No. of Seeds 2 No. of Other Members 19
Family Centroid CFAMM00231169 Functional Category Investigative Drug with Natural Product
Superfamily Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 Inhibitor Tebufelone Superfamily
Class Class 121

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Diflunisal Family 7 421
Fatty-acid amide hydrolase 1 Inhibitor Propofol Family 5 428
Prostaglandin G/H synthase 1 Inhibitor Salicyclic Acid Family 3 39
Vitamin K epoxide reductase complex subunit 1 Inhibitor Warfar... 9 508
Estrogen receptor beta Ligand Conjugated Estrogens Family 12 210
Oestrogen receptor ligand Dienestrol Family 35 440
Vitamin K-dependent gamma-carboxylase Inhibitor Anisindione Fa... 3 243
Danthron family 11 141
Agrimophol family 10 22
Mitogen-activated protein kinase 12 Inhibitor SCIO-469 Family 1 7
Bile acid receptor Ligand SR-45023A (apomine) Family 3 34
Macrophage migration inhibitory factor and Prothrombin Inhibit... 2 49
Proto-oncogene tyrosine-protein kinase Src Inhibitor RU78299 F... 2 1
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
Steryl-sulfatase Inhibitor Sulfamic Acid 3-(4-hydroxy-benzoyl)... 3 2
Epidermal growth factor receptor Ligand AG-538 Family 5 11
Estrogen receptor beta Ligand 3,6-dihydroxy-2-(4-hydroxy-pheny... 2 23
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 2 32
4-aminobutyrate aminotransferase, mitochondrial and Succinate-... 4 22
L-selectin and P-selectin Inhibitor 2,3,4-trihydroxybenzoic Ac... 2 10
Tyrosine-protein phosphatase non-receptor type 1 Ligand Licoag... 9 32
Cytosolic phospholipase A2 Inhibitor [6,3''']biflavone Family 5 5
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-(6-hydroxy-2-nap... 7 9
Arachidonate 12-lipoxygenase, 12S-type and Arachidonate 15-lip... 3 7
Tyrosine-protein phosphatase non-receptor type 1 Ligand Kuwano... 3 3
Amine oxidase [flavin-containing] B Inhibitor 3-(4-methoxyphen... 3 29
Tyrosinase Inhibitor 3-(2,4-dihydroxyphenyl)-propionic Acid Et... 3 8
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 14
Thromboxane A2 receptor ligand AGN-PC-003UTI family 1 0
Steryl-sulfatase inhibitor (8R,9S,13S,14S,17R)-17-benzyl-3,17-... 1 1
Catechol O-methyltransferase inhibitor 4,5-dihydroxybenzene-1,... 1 1
Eukaryotic elongation factor 2 kinase and Proto-oncogene tyros... 1 1
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 1 3
Benzoic Acid and Derivatives Metabolite Methyl 3-(2,3-dihydrox... 1 3
Acenes Metabolite Lacinilene C Family 2 3
Prenol Lipids Metabolite Macrocarpal B Family 3 0
Putative NP ZINC49600254 Family 8 2
2,4-diacetyl-5-hydroxy-3-(4-hydroxyphenyl)-5-methylcyclohexen-... 4 0
Putative NP ZINC03197541 Family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00231169 DNC003775 Investigative Drug TEBUFELONE
CFAMM00231181 DNC014755 Investigative Drug 4-Hydroxy-3,5-diisopropyl-benzaldehyde

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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