CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1188
Family Name D(2) dopamine receptor and D(3) dopamine receptor Ligand Benzyl-[2-(1h-indazol-4-yloxy)-ethyl]-amine Family
No. of Seeds 2 No. of Other Members 9
Family Centroid CFAMM00231230 Functional Category Investigative Drug
Superfamily D(2) dopamine receptor and D(3) dopamine receptor Binder Superfamily 4
Class Class 1308

Cousin Family NamesSeedsMembers
Sodium channel protein type 4 subunit alpha Ligand 3-(4-phenox... 2 4
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 50 36
Nitric oxide synthase, brain Inhibitor 7-methoxy-1h-indazole F... 1 1
Transient receptor potential cation channel subfamily V member... 7 17
Transient receptor potential cation channel subfamily V member... 2 1
Rho-associated protein kinase 2 inhibitor 1-ethyl-1-[(3-methox... 15 8
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 0
Cell division cycle 7-related protein kinase inhibitor SureCN4... 1 1
Mitogen-activated protein kinase 8 and Dual specificity protei... 1 1
Lanosterol synthase and Squalene--hopene cyclase inhibitor (2E... 2 0


External ID

Functional Category

Molecule Name

CFAMM00231227 CHEMBL225582 Bioactive SureCN5640737
CFAMM00231230 DNC003777 Investigative Drug Benzyl-[2-(1H-indazol-4-yloxy)-ethyl]-amine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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