CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1192
Family Name Platelet-derived growth factor receptor alpha and Platelet-derived growth factor receptor beta Ligand RPR-101511 Family
No. of Seeds 6 No. of Other Members 8
Family Centroid CFAMM00231311 Functional Category Investigative Drug with Natural Product
Superfamily Platelet-derived growth factor receptor alpha and Platelet-derived growth factor receptor beta Ligand RPR-101511 Superfamily
Class Class 2018

Cousin Family NamesSeedsMembers
DNA Binder Primaquine Family 3 245
Melatonin receptor type 1A Ligand Melatonin Family 20 988
Phospholipase A2 Inhibitor Quinacrine Family 13 95
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Hepatocyte growth factor receptor and Vascular endothelial gro... 28 178
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 13 22
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Estradiol 17-beta-dehydrogenase 1 Inhibitor 4'-(6-methoxypyrid... 5 34
Platelet-derived growth factor receptor alpha and Platelet-der... 2 17
Platelet-derived growth factor receptor alpha and Platelet-der... 2 9
Platelet-derived growth factor receptor beta and Epidermal gro... 3 7
Platelet-derived growth factor receptor alpha and Platelet-der... 2 14
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 12 3
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 6
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(1,5-naph... 4 20
Metabotropic glutamate receptor 5 Ligand 7-(3,5-dimethoxypheny... 2 7
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 2 5
Proto-oncogene tyrosine-protein kinase Src inhibitor SureCN525... 8 8
Proto-oncogene tyrosine-protein kinase Src inhibitor AC1NS5MA ... 3 4
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 16 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 3
RAC-alpha serine/threonine-protein kinase inhibitor N-[(2S)-1-... 2 1
D(2) dopamine receptor and D(4) dopamine receptor ligand AGN-P... 1 0
Melanin-concentrating hormone receptor 1 ligand (1S,3S)-1-N-(4... 3 9
Vascular endothelial growth factor receptor 2 and Platelet-der... 1 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 4
Indoles Metabolite 6-Methoxy-3-(2-thiazolyl)-1H-indole Family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00231313 DNC003803 Investigative Drug 6-Methoxy-3-thiophen-3-yl-quinoline
CFAMM00231311 DNC003826 Investigative Drug RPR-101511
CFAMM00231310 DNC003809 Investigative Drug 5,7-Dimethoxy-3-thiophen-3-yl-quinoline
CFAMM00231327 DNC003784 Investigative Drug 7-Methoxy-3-thiophen-3-yl-quinoline
CFAMM00231319 DNC003792 Investigative Drug 7-Thiophen-3-yl-[1,3]dioxolo[4,5-g]quinoline
CFAMM00231325 DNC003783 Investigative Drug 6,7-Dimethoxy-3-thiophen-2-yl-quinoline

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26816 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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