CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1198
Family Name Dual specificity mitogen-activated protein kinase kinase 1 Inhibitor Aldisin Family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00231446 Functional Category Investigative Drug with Human Metabolite
Superfamily Amine oxidase [flavin-containing] A and Dual specificity mitogen-activated protein kinase kinase 1 Binder Superfamily
Class Class 1390

Cousin Family NamesSeedsMembers
Cytochrome P450 11B1, mitochondrial Inhibitor Metyrapone Family 9 243
Cyclin-dependent kinase 1 Inhibitor 10z-hymenialdisine Family 3 3
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 1-(9h-... 4 25
Poly [ADP-ribose] polymerase 1 Inhibitor 1,7,8,9-tetrahydro-1,... 19 64
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 24 50
M-phase inducer phosphatase 2 Inhibitor 6,7-dibromoquinoline-5... 1 2
Amine oxidase [flavin-containing] A Inhibitor N-benzyl-1h-pyrr... 12 46
Sodium-dependent serotonin transporter and Sodium-dependent do... 10 2
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 3 12
D(3) dopamine receptor and D(2) dopamine receptor ligand (7S)-... 2 19
72 kDa type IV collagenase and Interstitial collagenase inhibi... 1 1
Naphthyridines Metabolite 3-Acetyl-2,7-naphthyridine Family 1 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00231441 DNC008601 Investigative Drug 1H-indole-4,7-dione
CFAMM00231446 DNC003817 Investigative Drug ALDISIN

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27526 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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