CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1205
Family Name 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor Bexlosteride Family
No. of Seeds 5 No. of Other Members 23
Family Centroid CFAMM00231759 Functional Category Investigative Drug
Superfamily 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor Bexlosteride Superfamily
Class Class 2022

Cousin Family NamesSeedsMembers
Neuromedin-K receptor Ligand Osanetant Family 38 192
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-m... 8 37
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 5-(4-chloro-... 10 52
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 9 66
Aminopeptidase N Inhibitor N1-(4-chlorobenzyl)-2-benzyl-n3-hyd... 9 86
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-3'... 14 11
Kappa-type opioid receptor ligand 1-[(2S)-2-(pyrrolidin-1-ylme... 4 0
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 1 18
Substance-P receptor ligand AGN-PC-075NUD family 4 1
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor lig... 2 0
Pyruvate kinase PKM and Huntingtin inhibitor CHEMBL1455935 family 1 3
Nociceptin receptor and Kappa-type opioid receptor ligand Pipe... 1 0
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 2 6
Sodium-dependent dopamine transporter and Transporter inhibito... 6 0
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 1 3
Substance-P receptor ligand 1-benzyl-3-[bis(4-chlorophenyl)met... 1 3
3-oxo-5-alpha-steroid 4-dehydrogenase 1 inhibitor 8-bromo-4-me... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00231769 CHEMBL279131 Bioactive 148905-78-6
CFAMM00231762 CHEMBL24955 Bioactive Bexlosteride
CFAMM00231754 CHEMBL417109 Bioactive (10bR)-8-chloro-4,10b-dimethyl-2,4a,5,6-tetrahydro-1H-benzo[f]quinolin-3-one
CFAMM00231771 DNC003973 Investigative Drug LY-266111
CFAMM00231759 DNC003843 Investigative Drug Bexlosteride

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48705 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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