CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1207
Family Name 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 4-methyl-5,6-dihydro-pyrido[1,2-a]quinolin-3-one Family
No. of Seeds 3 No. of Other Members 12
Family Centroid CFAMM00231799 Functional Category Investigative Drug
Superfamily 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 4-methyl-5,6-dihydro-pyrido[1,2-a]quinolin-3-one Superfamily
Class Class 2023

Cousin Family NamesSeedsMembers
Tumor necrosis factor Inhibitor Pirfenidone Family 2 38
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
K-604 family 4 71
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Fumarate reductase flavoprotein subunit Inhibitor 2-heptyl-4-h... 3 16
Liver carboxylesterase 1 Inhibitor 1-methyl-1h-indole-2,3-dion... 10 35
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
Aldose reductase Inhibitor (4-methyl-2-oxo-2h-quinolin-1-yl)-a... 1 15
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
3-oxo-5-alpha-steroid 4-dehydrogenase 1 inhibitor 8-bromo-4-me... 1 0
3-oxo-5-alpha-steroid 4-dehydrogenase 1 inhibitor AGN-PC-006C4... 1 1
3-oxo-5-alpha-steroid 4-dehydrogenase 1 inhibitor SureCN681575... 2 9
Thyroid hormone receptor beta and DNA-(apurinic or apyrimidini... 1 0
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 8 1
Amyloid beta A4 protein inhibitor AGN-PC-08WTQK family 1 3
Prelamin-A/C and Beta-lactamase inhibitor AE-562/12222510 family 1 9
Acetylcholinesterase inhibitor tmtfa family 1 2
3-prop-2-enyl-1H-quinolin-4-one NP 6-amino-2-methylquinolin-4-... 5 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00231802 DNC003846 Investigative Drug 1,2,5,6-tetrahydro pyrido[1,2-a]quinolin-3-one
CFAMM00231801 DNC003862 Investigative Drug 3,4,5,6-Tetrahydrobenzo[c]quinolizin-3-(4aH)-one
CFAMM00231799 DNC003941 Investigative Drug 4-Methyl-5,6-dihydro-pyrido[1,2-a]quinolin-3-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27419 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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