CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1221
Family Name Poly [ADP-ribose] polymerase 1 Inhibitor 2-(4-amino-phenyl)-8-methyl-3h-quinazolin-4-one Family
No. of Seeds 4 No. of Other Members 35
Family Centroid CFAMM00232636 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Poly [ADP-ribose] polymerase 1 Binder Superfamily 2
Class Class 2030

Cousin Family NamesSeedsMembers
Extracellular calcium-sensing receptor Ligand 3-phenethyl-2-ph... 3 137
Poly [ADP-ribose] polymerase 1 Inhibitor 5-chloro-2-methyl-3h-... 1 1
Poly [ADP-ribose] polymerase 1 Inhibitor 8-methyl-2-(4-nitro-p... 1 0
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 53
Urokinase plasminogen activator surface receptor ligand 5,12-d... 1 0
Histone deacetylase 6 and Histone deacetylase 8 inhibitor (E)-... 2 8
C-X-C chemokine receptor type 3 ligand N-[2-(dimethylamino)eth... 3 4
Niemann-Pick C1 protein and Ras-related protein Rab-9A inhibit... 1 3
Poly [ADP-ribose] polymerase 1 inhibitor 8-amino-1H-quinazolin... 1 2
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 1 0
quinazolin-4-one NP Megxm0 000086 Family 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00232646 DNC011693 Investigative Drug 2,8-Dimethyl-3H-quinazolin-4-one
CFAMM00232677 DNC011650 Investigative Drug 8-Methyl-2-phenyl-3H-quinazolin-4-one
CFAMM00232636 DNC011614 Investigative Drug 2-(4-Amino-phenyl)-8-methyl-3H-quinazolin-4-one
CFAMM00232658 DNC003879 Investigative Drug 3-Methyl-2H-benzo[f]quinazolin-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45058 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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