CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1224
Family Name cGMP-inhibited 3',5'-cyclic phosphodiesterase A and Potassium voltage-gated channel subfamily H member 2 Ligand Vesnarinone Family
No. of Seeds 1 No. of Other Members 15
Family Centroid CFAMM00232714 Functional Category Investigative Drug with Natural Product
Superfamily Multidrug resistance protein 1 and Multidrug resistance-associated protein 1 Binder Superfamily
Class Class 1059

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Histamine H1 receptor Ligand Tranilast Family 5 125
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
Oxytocin receptor and Vasopressin V1a receptor Ligand L-371257... 8 92
Substance-K receptor Ligand MEN-14933 Family 13 154
Mitogen-activated protein kinase 14 and Serine/threonine-prote... 1 1
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Multidrug resistance protein 1 and Multidrug resistance-associ... 3 55
Urotensin-2 receptor Ligand JNJ-28318706 Family 4 227
Proto-oncogene tyrosine-protein kinase receptor Ret Ligand (z)... 1 60
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Amine oxidase [flavin-containing] A and Mitogen-activated prot... 1 71
D(2) dopamine receptor Ligand Epidepride Family 31 66
Liver carboxylesterase 1 Inhibitor SCH-48375 Family 2 28
Cannabinoid receptor 2 ligand 8-butoxy-N-(2-fluoro-2-phenyleth... 12 7
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 49 8
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 9
Cystic fibrosis transmembrane conductance regulator inhibitor ... 2 3
Melanin-concentrating hormone receptor 1 and Potassium voltage... 3 6
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial ... 3 3
Integrin beta-3 and Integrin alpha-2 inhibitor 3-(4-methoxyphe... 4 6
Bifunctional epoxide hydrolase 2 inhibitor 3-[4-[[4-(trifluoro... 5 22
Delta-type opioid receptor and Kappa-type opioid receptor liga... 5 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
P2X purinoceptor 7 inhibitor N-[1-[(Z)-[(cyanoamino)-(2,4-difl... 3 26
Mitogen-activated protein kinase 14 inhibitor SureCN6679437 fa... 1 0
Coagulation factor X inhibitor 3,4-dimethoxy-N-[N-(4-methoxyph... 3 0
Histone deacetylase 1 and Histone deacetylase 2 inhibitor 4-[3... 4 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 0
dimethyl 5-[[2-(3,4,7,8,9,10-hexahydro-2H-[1,4]dioxepino[2,3-g... 1 0
(3R)-6,7-dimethoxy-1,2,3,4-tetrahydroquinoline-3-carboxylate N... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00232714 DNC003894 Investigative Drug VESNARINONE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

23724 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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