CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1228
Family Name cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor CI-930 Family
No. of Seeds 3 No. of Other Members 13
Family Centroid CFAMM00232807 Functional Category Investigative Drug
Superfamily cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor CI-930 Superfamily
Class Class 86

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
Tubulin beta chain Inhibitor Mebendazole Family 12 84
Prothrombin Inhibitor Dabigatran Family 7 182
Thromboxane-A synthase Inhibitor CGS-13080 Family 3 19
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 45
Metabotropic glutamate receptor 5 Ligand 3-cyano-5-fluoro-n-(p... 2 9
Platelet-activating factor receptor ligand SureCN9384429 family 11 3
Melanin-concentrating hormone receptor 1 ligand AGN-PC-088XRP ... 2 10
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... 7 29
Metabotropic glutamate receptor 2 ligand AGN-PC-09QJ9P family 2 7
Metabotropic glutamate receptor 2 ligand AGN-PC-01XRTW family 1 0
Cytochrome P450 26A1 and Cytochrome P450 3A4 inhibitor AGN-PC-... 5 17
Cytochrome P450 11B1, mitochondrial and Cytochrome P450 11B2, ... 3 4
Cdc2-related kinase inhibitor N-[6-(3,5-dimethylphenyl)-1-meth... 1 0
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
Metabotropic glutamate receptor 2 ligand 8-(2,5-difluorophenyl... 6 2
Metabotropic glutamate receptor 2 ligand 8-[2-(4-fluorophenyl)... 2 3
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 2 0


External ID

Functional Category

Molecule Name

CFAMM00232807 DNC003901 Investigative Drug CI-930
CFAMM00232816 DNC004281 Investigative Drug IMAZODAN
CFAMM00232825 DNC004302 Investigative Drug TETRAHYDROBENXIMIDAZOLE

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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