CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1231
Family Name Integrin beta-3 Inhibitor Sibrafiban Family
No. of Seeds 4 No. of Other Members 6
Family Centroid CFAMM00232864 Functional Category Investigative Drug
Superfamily Prothrombin and Integrin beta-3 Binder Superfamily
Class Class 1715

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor Ximelagatran Family 5 48
Integrin alpha-V and Integrin beta-3 Inhibitor C[rgd-(s)-alpha... 19 95
Neuromedin-K receptor Ligand Senktide Family 15 22
Integrin alpha-V and Integrin beta-3 Inhibitor Cyclo-[-arg-gly... 5 38
Plasmepsin-2 Inhibitor PS-222036 Family 12 134
Integrin beta-3 Inhibitor L-709780 Family 9 10
Integrin beta-3 Inhibitor DMP-728 Family 3 0
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 6 24
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 3 21
Tryptase alpha/beta-1 and Tryptase delta inhibitor (2S,3R)-1-b... 3 4
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7285564... 1 2
Integrin beta-3 and Integrin alpha-IIb inhibitor (3S)-6-[[2-(4... 2 11
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7301018... 4 3
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7961093... 1 0
Caspase-1 and Caspase-8 inhibitor (4S,7S,11aS)-7-benzamido-N-[... 7 18
Integrin beta-3 and Integrin alpha-V inhibitor 2-[(1R,5S,11S,1... 8 2
Integrin beta-3 and Integrin alpha-IIb inhibitor AGN-PC-074AY6... 1 0
Caspase-1 inhibitor (3S)-3-[[(4S,7S)-7-[(2-fluorobenzoyl)amino... 4 0
Tryptase alpha/beta-1 and Tryptase delta inhibitor (2S,3R)-1-[... 8 0
Integrin beta-3 and Integrin alpha-IIb inhibitor AGN-PC-0757VU... 13 39


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00232871 CHEMBL435176 Bioactive Ro-48-3657
CFAMM00232870 CHEMBL310081 Bioactive SureCN6157636
CFAMM00232873 DNC004271 Investigative Drug RO-44-3888
CFAMM00232864 DNC003909 Investigative Drug SIBRAFIBAN

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27511 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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