CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1241
Family Name Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor Ligand SNAP-5150 Family
No. of Seeds 19 No. of Other Members 32
Family Centroid CFAMM00233123 Functional Category Investigative Drug
Superfamily Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor Ligand SNAP-5150 Superfamily
Class Class 2038

Cousin Family NamesSeedsMembers
Calcium channel ligand dihydropyridine derivative Nicardipine ... 10 16
Mu-type opioid receptor Ligand Anileridine Family 3 18
Vasopressin-neurophysin 2-copeptin Inhibitor Niravoline Family 7 45
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Alpha-1A adrenergic receptor Ligand SNAP-6201 Family 41 94
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 11 20
D(4) dopamine receptor ligand AGN-PC-074VC9 family 2 3
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 5 7
Sodium-dependent serotonin transporter and Sodium-dependent do... 2 1
Sigma non-opioid intracellular receptor 1 ligand 2-(2-nitrophe... 2 5
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 4 0
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 1 0
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 4 0
C-C chemokine receptor type 5 ligand N-[1-[(3R)-4-[benzenesulf... 3 2
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 1 0
Substance-P receptor ligand 3-[bis(4-fluorophenyl)methyl]-1-[(... 1 0


External ID

Functional Category

Molecule Name

CFAMM00233129 CHEMBL95548 Bioactive AGN-PC-074R9V
CFAMM00233114 CHEMBL432026 Bioactive AGN-PC-074R9P
CFAMM00233121 CHEMBL98063 Bioactive 2-(2-azidoethoxymethyl)-3-N-[3-(4,4-diphenylpiperidin-1-yl)propyl]-6-ethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxamide
CFAMM00233149 CHEMBL95578 Bioactive AGN-PC-074R9Q
CFAMM00233113 CHEMBL95290 Bioactive AGN-PC-074R9O
CFAMM00233140 CHEMBL323579 Bioactive AGN-PC-075D3L
CFAMM00233133 CHEMBL355910 Bioactive ethyl 1-[3-[[2,6-dimethyl-5-(methylcarbamoyl)-4-(4-nitrophenyl)-1,4-dihydropyridine-3-carbonyl]amino]propyl]-4-phenylpiperidine-4-carboxylate
CFAMM00233126 CHEMBL316495 Bioactive AGN-PC-074R6M
CFAMM00233139 CHEMBL279436 Bioactive 5-N-[3-(4,4-diphenylpiperidin-1-yl)propyl]-2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxamide
CFAMM00233153 CHEMBL95253 Bioactive AGN-PC-074RAB
CFAMM00233131 CHEMBL95736 Bioactive AGN-PC-074R6A
CFAMM00233137 CHEMBL180561 Bioactive SNAP-5150
CFAMM00233152 CHEMBL95434 Bioactive AGN-PC-074R8C
CFAMM00233130 CHEMBL99864 Bioactive AGN-PC-074REK
CFAMM00233109 CHEMBL151878 Bioactive ethyl 1-[3-[[5-carbamoyl-2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3-carbonyl]amino]propyl]-4-phenylpiperidine-4-carboxylate
CFAMM00233128 DNC003939 Investigative Drug SNAP-5089
CFAMM00233118 DNC004932 Investigative Drug (-)-SNAP-5399
CFAMM00233123 DNC004177 Investigative Drug SNAP-5150

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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