CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1249
Family Name Somatostatin receptor type 1 Ligand Des-aa1,2,5-[(nalphame)lys4,d-nal8,iamp9]srif Family
No. of Seeds 16 No. of Other Members 11
Family Centroid CFAMM00233248 Functional Category Investigative Drug
Superfamily Genome polyprotein and Delta-type opioid receptor Binder Superfamily
Class Class 2006

Cousin Family NamesSeedsMembers
Bacterial outer membrane Inhibitor Polymyxin B Family 17 181
B1 bradykinin receptor Ligand B-9858 Family 4 14
B1 bradykinin receptor Ligand B-9958 Family 6 4
Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Beta-secretase 1 Inhibitor MMI-175 Family 30 137
Proto-oncogene tyrosine-protein kinase Src Inhibitor Y-c[d-pen... 20 66
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Nociceptin receptor Ligand Fggftgcrkscrk Family 10 0
Calcitonin gene-related peptide type 1 receptor Ligand Fvptdvg... 8 8
Proto-oncogene tyrosine-protein kinase Src Inhibitor Ac-cys-il... 36 12
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 31 5
Mu-type opioid receptor and Nociceptin receptor Ligand Ac-ryyr... 60 11
Beta-secretase 1 Inhibitor KMI-172 Family 3 0
C-X-C chemokine receptor type 4 Ligand Cyclo(-d-tyr-l-ala-l-ar... 25 23
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 6 24
Disks large homolog 4 Inhibitor N-(3,4-difluorophenyl)propyl-e... 3 0
Substance-P receptor Ligand [sar9,met(o2)11]-sp Family 34 9
Integrin alpha-V Inhibitor C[rgdf-(3s)-carboxymorpholine] Family 10 2
Caspase-4 and Cathepsin D Inhibitor Grassystatin A Family 24 6
Genome polyprotein Inhibitor Acasp-glu-dif-ile-cha-cys-iqc-nle... 9 0
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 152 36
Sodium-dependent dopamine transporter Inhibitor Bip-tyr-thr-pr... 8 2
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 48 10
Mu-type opioid receptor and Nociceptin receptor Ligand Nocicep... 35 5
Melanocortin receptor 4 and Melanocyte-stimulating hormone rec... 3 10
Pol polyprotein inhibitor penicillin deriv. 69 family 1 1
Renin and Cathepsin D inhibitor (3S)-4-[[6-acetamido-2-[[3-nap... 6 26
Endothelin-converting enzyme 1 and Cathepsin D inhibitor N-[(2... 6 2
Beta-secretase 1 inhibitor (2S)-2-[(3R)-3-acetamido-3-(2-methy... 3 0
Somatostatin receptor type 1 and Somatostatin receptor type 4 ... 2 0
Pol polyprotein inhibitor AC1L9R8I family 1 0
Somatostatin receptor type 2 and Somatostatin receptor type 3 ... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00233239 CHEMBL1824051 Bioactive CHEMBL1824051
CFAMM00233238 CHEMBL1824052 Bioactive CHEMBL1824052
CFAMM00233252 DNC004735 Investigative Drug Des-AA1,2,5-[D-Nal8,IAmp9,(NalphaMe)Ser13]SRIF
CFAMM00233251 DNC004734 Investigative Drug Des-AA1,2,5-[D-Nal8,IAmp9,(NalphaMe)Thr12]SRIF
CFAMM00233231 DNC003960 Investigative Drug Y-c[D-Pen-D-(2')Nal-GSFC]KR-NH2
CFAMM00233250 DNC004737 Investigative Drug Des-AA1,2,5-[D-Nal8,IAmp9,(NalphaMe)Cys14]SRIF
CFAMM00233236 DNC004728 Investigative Drug Des-AA1,2,5-[D-Nal8,IAmp9]SRIF
CFAMM00233249 DNC004731 Investigative Drug Des-AA1,2,5-[(NalphaMe)D-Nal8,IAmp9]SRIF
CFAMM00233235 DNC004729 Investigative Drug Des-AA1,2,5-[(NalphaMe)Cys3,D-Nal8,IAmp9]SRIF
CFAMM00233248 DNC004730 Investigative Drug Des-AA1,2,5-[(NalphaMe)Lys4,D-Nal8,IAmp9]SRIF
CFAMM00233241 DNC003959 Investigative Drug Y-c[D-Pen-(2')Nal-GSFC]KR-NH2
CFAMM00233247 DNC004733 Investigative Drug Des-AA1,2,5-[D-Nal8,IAmp9,(NalphaMe)Phe11]SRIF
CFAMM00233246 DNC004732 Investigative Drug Des-AA1,2,5-[D-Nal8,(NalphaMe)IAmp9]SRIF

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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