CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1258
Family Name Cruzipain Inhibitor 5-chloro-1-(4-chloro-benzyl)-1h-indole-2,3-dione Family
No. of Seeds 3 No. of Other Members 13
Family Centroid CFAMM00233659 Functional Category Investigative Drug with Natural Product
Superfamily Liver carboxylesterase 1 and Cruzipain Binder Superfamily
Class Class 1607

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(3) dopamine receptor ligand indol... 4 123
Tumor necrosis factor Inhibitor Thalidomide Family 3 50
Serum albumin Inhibitor Ebselen Family 3 62
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Fumarate reductase flavoprotein subunit Inhibitor 2-heptyl-4-h... 3 16
Liver carboxylesterase 1 Inhibitor 1-methyl-1h-indole-2,3-dion... 10 35
Liver carboxylesterase 1 Inhibitor 4-chloro-1h-indole-2,3-dion... 3 7
Liver carboxylesterase 1 Inhibitor 7-chloro-1h-indole-2,3-dion... 6 5
Liver carboxylesterase 1 Inhibitor 7-(trifluoromethyl)-1h-indo... 1 1
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 7 35
Oxysterols receptor LXR-alpha Ligand 2-(2-phenethylphenyl)isoi... 4 7
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 12
Muscarinic acetylcholine receptor M5 Ligand VU0119498 Family 1 3
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
3-oxo-5-alpha-steroid 4-dehydrogenase 1 inhibitor SureCN681575... 2 9
Vasopressin V2 receptor ligand [2-chloro-4-(prop-2-enylamino)p... 3 14
Cellular tumor antigen p53 and Inositol monophosphatase 1 inhi... 1 12
Protease and Replicase polyprotein 1a inhibitor AC1LALLS family 1 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 8
D(4) dopamine receptor and 5-hydroxytryptamine receptor 2A lig... 1 4
Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3... 2 0
Tubulin beta-2B chain and Similar to alpha-tubulin isoform 1 i... 1 0
4,4,6,9-tetramethyl-6-phenyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]q... 5 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00233662 DNC007179 Investigative Drug 1-(3,4-dichlorobenzyl)-1H-indole-2,3-dione
CFAMM00233650 DNC007180 Investigative Drug 1-(4-chlorobenzyl)-1H-indole-2,3-dione
CFAMM00233659 DNC003995 Investigative Drug 5-Chloro-1-(4-chloro-benzyl)-1H-indole-2,3-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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