CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1261
Family Name Androgen receptor Ligand LG-121071 Family
No. of Seeds 8 No. of Other Members 32
Family Centroid CFAMM00233727 Functional Category Investigative Drug with Natural Product
Superfamily Androgen receptor Ligand LG-121071 Superfamily
Class Class 2044

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Sodium channel Ligand xylidine derivative Mepivacaine Family 10 114
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 10 157
Motilin receptor Ligand GSK962040 Family 30 457
Tumor necrosis factor Inhibitor Pirfenidone Family 2 38
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Aromatase Inhibitor 3-(4-amino-phenyl)-1-methyl-pyrrolidine-2,... 4 8
Transient receptor potential cation channel subfamily V member... 6 33
Androgen receptor Ligand 6-n-propyl -4-trifluoromethylquinolin... 29 13
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Amine oxidase [flavin-containing] B Inhibitor L-136662 Family 3 20
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 42
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 9h-bet... 1 1
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 4 24
Aldose reductase Inhibitor (4-methyl-2-oxo-2h-quinolin-1-yl)-a... 1 15
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 10
Androgen receptor and Progesterone receptor ligand (5bR,9aR)-1... 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-(1-... 1 0
Transient receptor potential cation channel subfamily V member... 1 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-cyc... 2 1
Nociceptin receptor and Mu-type opioid receptor ligand N,N-dim... 5 4
Melanin-concentrating hormone receptor 1 and Potassium voltage... 2 2
Androgen receptor ligand 6-[(2R,5R)-2-methyl-5-[(1S)-2,2,2-tri... 2 0
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 6
5-hydroxytryptamine receptor 7 ligand 3-ethyl-3-[4-[4-(4-fluor... 3 1
Substance-P receptor ligand N-[[3,5-bis(trifluoromethyl)phenyl... 1 0
Dipeptidyl peptidase 4 inhibitor (2S,4S)-1-[2-[[1-[4-cyano-2-(... 2 0
5-hydroxytryptamine receptor 4 ligand 2-oxo-N-[(1R,5S)-8-(2-pi... 13 5
D(1A) dopamine receptor and D(3) dopamine receptor ligand 1-[4... 1 0
Acyl-CoA:cholesterol acyltransferase inhibitor N-[2,6-di(propa... 1 2
Metabotropic glutamate receptor 2 ligand 4-[4-(methylamino)phe... 1 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00233718 CHEMBL348918 Bioactive (2R,3R)-2,3,8-trimethyl-5-(trifluoromethyl)-2,3-dihydro-1H-pyrrolo[3,2-g]quinolin-7-one
CFAMM00233731 CHEMBL163425 Bioactive (5bR,9aR)-1-methyl-4-(trifluoromethyl)-6,7,8,9,9a,10-hexahydro-5bH-pyrido[2,3-b]carbazol-2-one
CFAMM00233737 CHEMBL27297 Bioactive AGN-PC-073GQY
CFAMM00233710 CHEMBL163366 Bioactive (2R)-2,8-dimethyl-5-(trifluoromethyl)-2,3-dihydro-1H-pyrrolo[3,2-g]quinolin-7-one
CFAMM00233723 CHEMBL422196 Bioactive (5bR,9aR)-1,5b-dimethyl-4-(trifluoromethyl)-6,7,8,9,9a,10-hexahydropyrido[2,3-b]carbazol-2-one
CFAMM00233741 CHEMBL160230 Bioactive 2-ethyl-1,2,9-trimethyl-6-(trifluoromethyl)-3,4-dihydropyrido[3,2-g]quinolin-8-one
CFAMM00233726 CHEMBL351519 Bioactive (2R)-2,3,3,8-tetramethyl-5-(trifluoromethyl)-1,2-dihydropyrrolo[3,2-g]quinolin-7-one
CFAMM00233727 DNC003999 Investigative Drug LG-121071

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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