CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1270
Family Name Glucocorticoid receptor Ligand 1-methoxy-6-phenyl-6h-benzo[c]chromene Family
No. of Seeds 2 No. of Other Members 22
Family Centroid CFAMM00233951 Functional Category Investigative Drug with Natural Product
Superfamily Neuraminidase and Androgen receptor Binder Superfamily
Class Class 605

Cousin Family NamesSeedsMembers
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Cannabinoid receptor 1 Ligand Marinol Family 32 454
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Tyrosinase Inhibitor Monobenzone Family 6 197
Oestrogen receptor Ligand Chlorotrianisene Family 2 102
Ipriflavone family 62 2480
Salicin family 5 629
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
NAD-dependent protein deacetylase sirtuin-1 Inhibitor SRT501 F... 19 88
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Melatonin receptor type 1A Ligand Agomelatine Family 12 164
Glucokinase Inhibitor R7201 Family 22 105
Translocator protein Inhibitor Dextofisopam Family 3 250
Oxi4503 family 4 27
TS-071 family 8 36
Platelet-activating factor receptor Ligand L-652731 Family 5 116
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-(b... 4 42
Oestrogen receptor and Estrogen receptor beta Ligand 6-(4-hydr... 30 63
Abelson tyrosine-protein kinase 2 Inhibitor 3'',5''-dimethoxy-... 3 9
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 5 13
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 127
Tubulin beta chain Inhibitor Combretastatin Family 3 5
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 214
NAD(P)H dehydrogenase [quinone] 1 Inhibitor NSC-106547 Family 3 65
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 4-(1,... 3 31
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 160
Kappa-type opioid receptor Ligand Anisocoumarin H Family 3 5
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 4 37
5-hydroxytryptamine receptor 2A Ligand 3-methoxy-9-aminomethyl... 7 14
Androgen receptor Ligand 2-methoxy-4-(o-tolyloxy)benzonitrile ... 5 12
Thyroid hormone receptor alpha and Thyroid hormone receptor be... 5 8
MO15-related protein kinase Pfmrk Inhibitor WR-289012 Family 2 17
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
NAD(P)H dehydrogenase [quinone] 1 Inhibitor Ethyl Bis(4-hydrox... 5 7
Indoleamine 2,3-dioxygenase 1 Inhibitor Naphthalene-1,4-diol F... 2 4
Amine oxidase [flavin-containing] B Inhibitor 7-fluoro-2-p-tol... 4 11
Tyrosine-protein phosphatase non-receptor type 1 and Neuramini... 10 2
Cytochrome P450 3A4 Inhibitor Diethoxyflourescein Family 3 9
Prostaglandin G/H synthase 1 Inhibitor 2-(2-methoxyphenyl)-1h-... 1 11
Tyrosinase Inhibitor 4-(6-hydroxynaphthalen-2-yl)benzene-1,3-d... 4 2
Androgen receptor Ligand Palodesangren E Family 12 43
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 3 27
Sodium/glucose cotransporter 2 and Sodium/glucose cotransporte... 3 19
Melatonin receptor type 1A ligand N-[(7-methoxynaphthalen-1-yl... 1 0
Vitamin D3 receptor ligand (3E,5E)-6-[3-[[3,4-bis(hydroxymethy... 2 4
5-hydroxytryptamine receptor 7 and Alpha-2C adrenergic recepto... 3 0
Steroidogenic factor 1 and Nuclear receptor subfamily 5 group ... 1 1
ahydropyrano[3,2-c]chromene NP ZINC04023039 Family 16 2
4-(9H-xanthen-9-yl)-9H-xanthene NP 9h,9'h-4,9'-bixanthene Family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00233951 DNC004018 Investigative Drug 1-Methoxy-6-phenyl-6H-benzo[c]chromene
CFAMM00233943 DNC011486 Investigative Drug 1,8,9-Trimethoxy-9,10-dihydro-anthracene

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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