CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1273
Family Name Steryl-sulfatase Inhibitor Sulfamic Acid 3-(4-hydroxy-benzoyl)-phenyl Ester Family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00233974 Functional Category Investigative Drug with Human Metabolite
Superfamily Steryl-sulfatase Binder Superfamily
Class Class 121

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Diflunisal Family 7 421
Prostaglandin G/H synthase 1 Inhibitor Salicyclic Acid Family 3 39
Vitamin K epoxide reductase complex subunit 1 Inhibitor Warfar... 9 508
Estrogen receptor beta Ligand Conjugated Estrogens Family 12 210
Oestrogen receptor ligand Dienestrol Family 35 440
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Aldehyde oxidase Inhibitor Isovanillin Family 6 429
Ipriflavone family 62 2480
Danthron family 11 141
Agrimophol family 10 22
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Mitogen-activated protein kinase 12 Inhibitor SCIO-469 Family 1 7
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Macrophage migration inhibitory factor and Prothrombin Inhibit... 2 49
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 I... 2 19
Steryl-sulfatase Inhibitor 3-{4-[(aminosulfonyl)oxy]benzoyl}ph... 5 3
Epidermal growth factor receptor Ligand AG-538 Family 5 11
Estrogen receptor beta Ligand 3,6-dihydroxy-2-(4-hydroxy-pheny... 2 23
Liver carboxylesterase 1 Inhibitor 1,2-bis(2,5-difluorophenyl)... 12 10
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2 3
4-aminobutyrate aminotransferase, mitochondrial and Succinate-... 4 22
L-selectin and P-selectin Inhibitor 2,3,4-trihydroxybenzoic Ac... 2 10
Tyrosine-protein phosphatase non-receptor type 1 Ligand Licoag... 9 32
Cytosolic phospholipase A2 Inhibitor [6,3''']biflavone Family 5 5
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-(6-hydroxy-2-nap... 7 9
Arachidonate 12-lipoxygenase, 12S-type and Arachidonate 15-lip... 3 7
Amine oxidase [flavin-containing] B Inhibitor (s)(+)-7-fluoro-... 11 11
Tyrosine-protein phosphatase non-receptor type 1 Ligand Kuwano... 3 3
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Tyrosinase Inhibitor 3-(2,4-dihydroxyphenyl)-propionic Acid Et... 3 8
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Isocitrate lyase Inhibitor Bis(3-bromo-4,5-dihydroxyphenyl)met... 1 2
Estrogen receptor beta and Estrogen receptor ligand 4-bromo-9a... 3 0
Thromboxane A2 receptor ligand AGN-PC-003UTI family 1 0
G2/mitotic-specific cyclin-B1 and Cyclin-dependent kinase 1 in... 2 8
Nuclear receptor ROR-gamma and Huntingtin ligand CHEMBL1568747... 1 3
Peroxisome proliferator-activated receptor gamma and Peroxisom... 1 2
Catechol O-methyltransferase inhibitor 4,5-dihydroxybenzene-1,... 1 1
Eukaryotic elongation factor 2 kinase and Proto-oncogene tyros... 1 1
Acenes Metabolite Lacinilene C Family 2 3
Putative NP ZINC49600254 Family 8 2
2,4-diacetyl-5-hydroxy-3-(4-hydroxyphenyl)-5-methylcyclohexen-... 4 0
Putative NP ZINC03197541 Family 1 0
2,4-bis(4-hydroxyphenyl)cyclobutane-1,3-dicarboxylate NP ZINC0... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00233975 DNC004026 Investigative Drug Sulfamic acid 3-(3-hydroxy-benzoyl)-phenyl ester
CFAMM00233974 DNC004030 Investigative Drug Sulfamic acid 3-(4-hydroxy-benzoyl)-phenyl ester
CFAMM00233973 DNC004056 Investigative Drug Sulfamic acid 4-(2-hydroxy-benzoyl)-phenyl ester

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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