CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1280
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 4-(2,5-diphenyl-furan-3-yl)-morpholine Family
No. of Seeds 4 No. of Other Members 31
Family Centroid CFAMM00234244 Functional Category Investigative Drug
Superfamily cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 4-(2,5-diphenyl-furan-3-yl)-morpholine Superfamily
Class Class 1685

Cousin Family NamesSeedsMembers
Mucosal addressin cell adhesion molecule 1 Inhibitor PF-005476... 64 96
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
Sodium channel protein type 10 subunit alpha Ligand A-803467 F... 2 81
Histamine H3 receptor Ligand A-317920 Family 9 240
Histamine H3 receptor Ligand A-349821 Family 49 228
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Amyloid beta A4 protein Inhibitor 6-iodo-4'-methylaminoflavone... 3 33
Leukotriene A-4 hydrolase Inhibitor N5-[4-(2-oxo-3-phenylpropo... 1 61
Macrophage migration inhibitory factor Inhibitor Benzofuran-2-... 5 67
Sodium channel protein type 10 subunit alpha and Sodium channe... 2 13
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 4 62
Tubulin beta chain Inhibitor Gnf-pf-117 Family 2 16
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 2 17
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 0
Sodium-dependent dopamine transporter and Sigma non-opioid int... 7 5
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 2 1
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 20 9
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 11 4
Lethal(3)malignant brain tumor-like protein 1 and Lysine-speci... 1 6
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 4 2
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 3 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand CHEMB... 13 20
MAP kinase-activated protein kinase 2 inhibitor 5-(4-cyanophen... 3 8
Cathepsin S and Cathepsin K inhibitor arylaminoethyl amide, 7 ... 2 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 1
Translocator protein inhibitor N-[(2,5-dimethoxyphenyl)methyl]... 1 0
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 4 6
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand CHEMB... 6 3
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 1 5
5-hydroxytryptamine receptor 1A ligand SureCN10513645 family 9 1
Delta-type opioid receptor and Kappa-type opioid receptor liga... 5 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Mu-type opioid receptor ligand AGN-PC-00NCMO family 3 1
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 1 1
Lanosterol synthase inhibitor AGN-PC-07BZTC family 1 3
Protein kinase C theta type and Protein kinase C epsilon type ... 1 0
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 1 2
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 1 0
P2Y purinoceptor 1 inhibitor AGN-PC-080TOG family 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00234229 CHEMBL543141 Bioactive AGN-PC-07BZHV
CFAMM00234222 CHEMBL545722 Bioactive AGN-PC-07BZHC
CFAMM00234221 CHEMBL545720 Bioactive AGN-PC-07BZHA
CFAMM00234244 DNC004039 Investigative Drug 4-(2,5-Diphenyl-furan-3-yl)-morpholine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26821 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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