CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1285
Family Name Glucocorticoid receptor Ligand 1-methoxy-6-phenyl-6h-benzo[c]chromen-8-ylamine Family
No. of Seeds 9 No. of Other Members 16
Family Centroid CFAMM00234310 Functional Category Investigative Drug
Superfamily Androgen receptor and Glucocorticoid receptor Binder Superfamily
Class Class 1999

Cousin Family NamesSeedsMembers
Mineralocorticoid receptor and Androgen receptor Ligand AL-43 ... 79 235
Mineralocorticoid receptor and Androgen receptor Ligand LGD-55... 6 6
Progesterone receptor and Glucocorticoid receptor ligand AGN-P... 6 2
Progesterone receptor and Glucocorticoid receptor ligand (5Z)-... 2 1
5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine recepto... 1 3
Androgen receptor ligand trifluoromethyl 10-methoxy-4-methyl-2... 2 57
Androgen receptor ligand 10-(hydroxymethyl)-4-methyl-1,5-dihyd... 2 2
Glucocorticoid receptor and Progesterone receptor ligand N-(1-... 1 1
Glucocorticoid receptor ligand N-[6-(3,4-dichlorophenyl)-1-met... 1 0
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 0


External ID

Functional Category

Molecule Name

CFAMM00234318 CHEMBL65354 Bioactive N-[6-(3-fluorophenyl)-1-methoxy-6H-benzo[c]chromen-8-yl]methanesulfonamide
CFAMM00234322 CHEMBL65868 Bioactive N-[1-methoxy-6-(4-methylphenyl)-6H-benzo[c]chromen-8-yl]methanesulfonamide
CFAMM00234309 CHEMBL65695 Bioactive N-[6-(3-chlorophenyl)-1-methoxy-6H-benzo[c]chromen-8-yl]methanesulfonamide
CFAMM00234321 CHEMBL304482 Bioactive N-[1-methoxy-6-(3-methoxyphenyl)-6H-benzo[c]chromen-8-yl]methanesulfonamide
CFAMM00234301 CHEMBL65221 Bioactive SureCN7235265
CFAMM00234319 CHEMBL304019 Bioactive N-[6-(4-chlorophenyl)-1-methoxy-6H-benzo[c]chromen-8-yl]methanesulfonamide
CFAMM00234310 DNC004052 Investigative Drug 1-Methoxy-6-phenyl-6H-benzo[c]chromen-8-ylamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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