CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1286
Family Name Oxytocin receptor and Vasopressin V1a receptor Ligand L-371257 Family
No. of Seeds 8 No. of Other Members 92
Family Centroid CFAMM00234331 Functional Category Investigative Drug with Natural Product
Superfamily Oxytocin receptor and Vasopressin V1a receptor Binder Superfamily
Class Class 2053

Cousin Family NamesSeedsMembers
SUR1-type K(ATP) channel and SUR2-type K(ATP) channel Ligand R... 1 16
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
cGMP-inhibited 3',5'-cyclic phosphodiesterase A and Potassium ... 1 15
Cytochrome P450 1B1 Inhibitor N-(2,4-dimethoxy-phenyl)-3,5-dim... 1 110
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Acetylcholinesterase and Cholinesterase Inhibitor 3-[7-(benzyl... 22 303
Alpha-1A adrenergic receptor and D(2) dopamine receptor Ligand... 5 49
Leukotriene A-4 hydrolase Inhibitor N5-[4-(2-oxo-3-phenylpropo... 1 61
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Urotensin-2 receptor Ligand JNJ-28318706 Family 4 227
Proto-oncogene tyrosine-protein kinase receptor Ret Ligand (z)... 1 60
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Oxytocin receptor and Vasopressin V1a receptor Ligand L-372662... 31 23
Acetylcholinesterase Inhibitor 6-methyl-4-(4-phenylpiperazin-1... 6 622
Liver carboxylesterase 1 Inhibitor SCH-48375 Family 2 28
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 6
C-C chemokine receptor type 3 ligand SureCN6705515 family 2 16
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 49 8
Acetylcholinesterase and Butyrylcholinesterase inhibitor [3-[[... 3 68
Neuropeptide S receptor and Prelamin-A/C ligand CHEMBL1352632 ... 1 25
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2C lig... 2 2
Multidrug resistance protein 1 inhibitor 1-[2-[(2R)-3-[4-(2,3-... 2 41
C5a anaphylatoxin chemotactic receptor 1 ligand N-[(4-dimethyl... 1 4
Vasopressin V1a receptor and Oxytocin receptor ligand 1-[1-[2-... 3 0
Bifunctional epoxide hydrolase 2 inhibitor 3-[4-[[4-(trifluoro... 5 22
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 1 5
Oxytocin receptor ligand SureCN8092936 family 2 0
Androgen receptor ligand trifluoromethyl 10-methoxy-4-methyl-2... 2 57
Delta-type opioid receptor and Kappa-type opioid receptor liga... 5 0
Retinoic acid receptor RXR-gamma and Retinoic acid receptor RX... 3 36
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 2 9
Hepatocyte growth factor receptor ligand 2-[(2-fluorophenyl)me... 6 11
Beta-secretase 1 inhibitor AGN-PC-00QBHE family 1 0
DNA-dependent protein kinase catalytic subunit inhibitor 5-hyd... 1 7
Acetylcholinesterase inhibitor 4-[(2-methoxyanilino)methyl]-[1... 2 4
Tyrosine-protein kinase ABL1 inhibitor N-(4-bromophenyl)-2-(5-... 1 3
Malate dehydrogenase, mitochondrial and Lactate dehydrogenase ... 1 1
Sodium channel protein type 1 subunit alpha and Sodium channel... 3 0
D(1A) dopamine receptor and D(3) dopamine receptor ligand 7-[3... 1 12
2-(1'-acetyl-4-oxospiro[3H-chromene-2,4'-piperidine]-7-yl)oxya... 5 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00234421 CHEMBL278818 Bioactive AGN-PC-01ZZKN
CFAMM00234413 CHEMBL24682 Bioactive AGN-PC-01ZZI6
CFAMM00234405 CHEMBL102994 Bioactive AGN-PC-074UXH
CFAMM00234397 CHEMBL24456 Bioactive SureCN8088545
CFAMM00234401 CHEMBL279230 Bioactive AGN-PC-073FS2
CFAMM00234414 CHEMBL24526 Bioactive SureCN8081394
CFAMM00234331 DNC004053 Investigative Drug L-371257

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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