CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1288
Family Name Leukotriene B4 receptor 1 Ligand SB-201993 Family
No. of Seeds 5 No. of Other Members 13
Family Centroid CFAMM00234455 Functional Category Investigative Drug
Superfamily Leukotriene B4 receptor 1 Binder Superfamily
Class Class 2052

Cousin Family NamesSeedsMembers
Arachidonate 5-lipoxygenase-activating protein Inhibitor DG031... 3 206
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 4 42
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
5-hydroxytryptamine receptor 1A Ligand Sun N4057 Family 2 86
Leukotriene B4 receptor 1 Ligand SB-209247 Family 7 24
Leukotriene B4 receptor 1 Ligand SB-201146 Family 3 18
Mu-type opioid receptor Ligand 6-(4-(2-(benzylamino)ethyl)phen... 3 27
Metabotropic glutamate receptor 1 Ligand JNJ-16259685 Family 3 20
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 10 4
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 4 20
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 18
Leukotriene B4 receptor 1 ligand SureCN8772238 family 1 1
Cysteinyl leukotriene receptor 1 ligand SureCN9053715 family 2 11
Insulin-like growth factor-binding protein 4 and Insulin-like ... 4 44
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
Leukotriene B4 receptor 1 ligand SureCN8987110 family 8 20
Leukotriene B4 receptor 1 ligand SureCN8987047 family 4 3
Cellular tumor antigen p53 inhibitor CHEMBL1395699 family 1 30
Arachidonate 5-lipoxygenase inhibitor (2E)-2-[2-butyl-1-[4-(qu... 1 12
Cysteinyl leukotriene receptor 2 and Cysteinyl leukotriene rec... 16 5
Cysteinyl leukotriene receptor 1 and Peripheral myelin protein... 1 1
Arachidonate 5-lipoxygenase-activating protein inhibitor methy... 12 3
Prostaglandin E synthase inhibitor 3-[4-(3-cyanopropoxy)-3-met... 2 4
Insulin-like growth factor-binding protein 3 inhibitor (1E)-1-... 2 0
Cysteinyl leukotriene receptor 1 ligand 4-oxo-7-[[3-(quinolin-... 4 17
Prothrombin and Trypsin-1 inhibitor AGN-PC-074I4I family 3 1
Thromboxane-A synthase inhibitor SureCN9045578 family 1 12
Ras guanyl-releasing protein 3 and Protein kinase C alpha type... 2 6
Testosterone 17-beta-dehydrogenase 3 and Estrogen receptor lig... 2 20
Testosterone 17-beta-dehydrogenase 3 inhibitor AGN-PC-04XS1Y f... 1 4
Lethal(3)malignant brain tumor-like protein 1 and Putative fru... 1 9
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN7... 1 0
Butyrylcholinesterase and Muscarinic acetylcholine receptor M2... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00234443 CHEMBL115658 Bioactive 3-[[6-[(E)-2-carboxyethenyl]-5-(4-phenylbutoxy)pyridin-2-yl]methylsulfanylmethyl]benzoic acid
CFAMM00234458 CHEMBL325637 Bioactive 4-[[6-[(E)-2-carboxyethenyl]-5-[8-(4-methoxyphenyl)octoxy]pyridin-2-yl]methylsulfanylmethyl]benzoic acid
CFAMM00234462 CHEMBL325773 Bioactive SureCN8078502
CFAMM00234461 CHEMBL112972 Bioactive 3-[[6-[(E)-2-carboxyethenyl]-5-[4-(4-methoxyphenyl)butoxy]pyridin-2-yl]methylsulfanylmethyl]benzoic acid
CFAMM00234455 DNC004058 Investigative Drug SB-201993

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27405 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543