CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1290
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor (2,5-diphenyl-furan-3-yl)-phenyl-methanone Family
No. of Seeds 1 No. of Other Members 9
Family Centroid CFAMM00234480 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor (2,5-diphenyl-furan-3-yl)-phenyl-methanone Superfamily
Class Class 1672

Cousin Family NamesSeedsMembers
Potassium voltage-gated channel subfamily H member 2 Ligand Am... 2 16
Cyclooxygenase inhibitor salicylate derivative Aspirin family 3 234
Vitamin K epoxide reductase complex subunit 1 Inhibitor Warfar... 9 508
DNA Binder Methoxsalen Family 10 1638
Vitamin K-dependent gamma-carboxylase Inhibitor Anisindione Fa... 3 243
Ipriflavone family 62 2480
Multidrug resistance-associated protein 1 Inhibitor Benzbromar... 2 16
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Estrogen receptor beta Ligand 2-(4-hydroxy-phenyl)benzofuran-5... 5 82
Cytosolic phospholipase A2 Inhibitor 1,1,1-trifluoro-6-(4-hexy... 9 86
Steryl-sulfatase Inhibitor Sulfamic Acid 4-(3-methoxy-benzoyl)... 5 24
Steryl-sulfatase Inhibitor Sulfamic Acid 2-nonyl-4-oxo-4h-chro... 4 68
Aromatase and DNA-dependent protein kinase catalytic subunit I... 6 19
Oestrogen receptor and Estrogen receptor beta Ligand 7-chloro-... 2 27
Phospholipase A2 Inhibitor 3,9-dihydroxy-2,10-diprenylpterocap... 9 25
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2 56
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2 3
Platelet-derived growth factor receptor beta Ligand Bis(5-meth... 5 220
Cytosolic phospholipase A2 Inhibitor [6,3''']biflavone Family 5 5
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Bifunctional epoxide hydrolase 2 Inhibitor 13-(5-n-pentylfuran... 1 80
Amine oxidase [flavin-containing] B Inhibitor (s)(+)-7-fluoro-... 11 11
Amine oxidase [flavin-containing] B Inhibitor 3-(4-methoxyphen... 3 29
Tyrosine-protein phosphatase non-receptor type 1 Ligand Formyl... 1 1
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 2-(3-c... 5 72
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 2-(3-b... 6 21
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Fatty-acid amide hydrolase 1 Inhibitor Benzofuran-2-ylboronic ... 1 14
Creatine kinase Inhibitor 5-(4'-benzoylbiphenyl-4-yl)-2-furoic... 2 66
Retinoic acid receptor RXR-alpha and Peroxisome proliferator-a... 3 17
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 1 1
Transient receptor potential M8 protein ligand 2-[1-diethoxyph... 1 0
Furans Metabolite Perilla ketone Family 2 5
Prenol Lipids Metabolite Furanogermenone Family 2 2
Naphthofurans Metabolite Pyrocurzerenone Family 1 9
NP 6-(4-ethoxyphenyl)-1,3-dimethyl-4-oxo-4h-cyclohepta[c]furan... 13 3
1,3-dimethylcyclohepta[c]furan-8-one NP 8-hydroxy-6-(4-methoxy... 10 0
5,6-dihydro-4H-furo[2',3':3,4]cyclohepta[1,2-b][1]benzofuran N... 3 0
2-methyl-2H-chromene-3-carbaldehyde NP 2-methyl-2h-chromene-3-... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00234480 DNC004063 Investigative Drug (2,5-Diphenyl-furan-3-yl)-phenyl-methanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27258 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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