CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1296
Family Name 72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhibitor RS-130830 Family
No. of Seeds 15 No. of Other Members 129
Family Centroid CFAMM00234737 Functional Category Investigative Drug
Superfamily 72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhibitor RS-130830 Superfamily
Class Class 2056

Cousin Family NamesSeedsMembers
Disintegrin and metalloproteinase domain-containing protein 17... 82 411
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 3 28
Disintegrin and metalloproteinase domain-containing protein 17... 25 33
Disintegrin and metalloproteinase domain-containing protein 17... 10 39
Collagenase 3 and Interstitial collagenase inhibitor N-hydroxy... 8 4
Collagenase 3 and Interstitial collagenase inhibitor AGN-PC-01... 10 1
Collagenase 3 and Interstitial collagenase inhibitor (1R,5S)-3... 2 1
Collagenase 3 and Interstitial collagenase inhibitor (3S)-3-[[... 5 1
72 kDa type IV collagenase and Collagenase 3 inhibitor N-hydro... 3 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 4-acety... 9 4
Collagenase 3 and Stromelysin-1 inhibitor 1-N-benzyl-3-N-hydro... 7 15
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-075O... 14 27
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R)-1-... 25 6
Macrophage metalloelastase and 72 kDa type IV collagenase inhi... 7 4
Collagenase 3 and 72 kDa type IV collagenase inhibitor AGN-PC-... 3 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 19 11
Disintegrin and metalloproteinase domain-containing protein 17... 6 12
72 kDa type IV collagenase and Collagenase 3 inhibitor 1-ethyl... 11 5
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 3 15
Disintegrin and metalloproteinase domain-containing protein 17... 5 2
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 2
Collagenase 3 and Interstitial collagenase inhibitor (3S,4R)-N... 9 8
Disintegrin and metalloproteinase domain-containing protein 17... 25 5
Collagenase 3 and 72 kDa type IV collagenase inhibitor 4-(4-ch... 7 6
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 0
Collagenase 3 and Neutrophil collagenase inhibitor (3R)-1-hydr... 1 0
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 7 1
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 3 0
Interstitial collagenase inhibitor AGN-PC-075XO4 family 1 0
Disintegrin and metalloproteinase domain-containing protein 17... 6 0
Disintegrin and metalloproteinase domain-containing protein 17... 3 16
Disintegrin and metalloproteinase domain-containing protein 17... 12 1
Disintegrin and metalloproteinase domain-containing protein 17... 9 3
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-[(4-b... 3 1
Disintegrin and metalloproteinase domain-containing protein 17... 2 0
72 kDa type IV collagenase and Disintegrin and metalloproteina... 5 1
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzy... 13 3
Macrophage metalloelastase and 72 kDa type IV collagenase inhi... 4 4
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzy... 6 2
Collagenase 3 and Matrix metalloproteinase-9 inhibitor N-hydro... 3 1
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 4-[4-[(... 5 1
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 3 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor 3-cyclo... 5 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 3 4
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00234808 CHEMBL1801044 Bioactive N-hydroxy-4-(4-phenoxyphenyl)sulfonyloxane-4-carboxamide
CFAMM00234795 CHEMBL1801053 Bioactive N-hydroxy-4-[4-(4-methylsulfanylphenoxy)phenyl]sulfonyloxane-4-carboxamide
CFAMM00234836 CHEMBL78549 Bioactive 4-[4-(4-chlorophenoxy)phenyl]sulfonyl-1-ethyl-N-hydroxypiperidine-4-carboxamide
CFAMM00234801 CHEMBL78337 Bioactive 4-[4-(4-chlorophenoxy)phenyl]sulfonyl-N-hydroxy-1-methylpiperidine-4-carboxamide
CFAMM00234815 CHEMBL1801049 Bioactive N-hydroxy-4-[4-(4-propan-2-yloxyphenoxy)phenyl]sulfonyloxane-4-carboxamide
CFAMM00234758 CHEMBL1770712 Bioactive AGN-PC-02W1K1
CFAMM00234799 CHEMBL1801054 Bioactive N-hydroxy-4-[4-[4-(trifluoromethylsulfanyl)phenoxy]phenyl]sulfonyloxane-4-carboxamide
CFAMM00234853 CHEMBL321257 Bioactive 4-[[4-(4-chlorophenoxy)phenyl]sulfonylamino]-N-hydroxyoxane-4-carboxamide
CFAMM00234811 CHEMBL1801047 Bioactive 4-[4-(3,4-dichlorophenoxy)phenyl]sulfonyl-N-hydroxyoxane-4-carboxamide
CFAMM00234810 CHEMBL1801046 Bioactive alpha-sulfone 21
CFAMM00234809 CHEMBL1801045 Bioactive 4-[4-(3-chlorophenoxy)phenyl]sulfonyl-N-hydroxyoxane-4-carboxamide
CFAMM00234850 CHEMBL310340 Bioactive 4-(4-butoxyphenyl)sulfonyl-N-hydroxyoxane-4-carboxamide
CFAMM00234830 CHEMBL80732 Bioactive 4-[4-(4-chlorophenoxy)phenyl]sulfonyl-N-hydroxypiperidine-4-carboxamide
CFAMM00234766 CHEMBL311357 Bioactive 1-butyl-4-[4-(4-chlorophenoxy)phenyl]sulfonyl-N-hydroxypiperidine-4-carboxamide
CFAMM00234737 DNC004074 Investigative Drug RS-130830

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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