CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Glycoprotein IIb/IIIa receptor Ligand Accutin Family
No. of Seeds 4 No. of Other Members 24
Family Centroid CFAMM00181990 Functional Category Investigative Drug with Human Metabolite
Superfamily Carbonic anhydrase 2 and Carbonic anhydrase 12 Binder Superfamily
Class Class 1420

Cousin Family NamesSeedsMembers
Tyrosinase Inhibitor Monobenzone Family 6 197
Oestrogen receptor ligand Dienestrol Family 35 440
NAD-dependent protein deacetylase sirtuin-1 Inhibitor SRT501 F... 19 88
Proto-oncogene tyrosine-protein kinase Src Inhibitor Phenylpho... 1 18
Thymidylate synthase Inhibitor 2-bromophenol Family 1 8
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor 1,4-ph... 3 9
Leukotriene A-4 hydrolase Inhibitor 1-butoxy-4-phenoxybenzene ... 3 85
Carbonic anhydrase 2 and Carbonic anhydrase 12 Inhibitor Resor... 2 7
Carbonic anhydrase 2 Inhibitor Guaiacol Family 1 14
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-meth... 4 12


External ID

Functional Category

Molecule Name

CFAMM00181974 DNC014801 Investigative Drug 3,5-difluorophenol
CFAMM00181990 DNC000142 Investigative Drug Accutin
CFAMM00181977 DNC005115 Investigative Drug phenoxyarsonous acid
CFAMM00181987 DNC014858 Investigative Drug 2,5-difluorophenol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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