CFam Chemical Families Database
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CFam Family Information

CFAM Family ID CFFID1300
Family Name Plasmepsin-1 Inhibitor SC-5003 Family
No. of Seeds 93 No. of Other Members 173
Family Centroid CFAMM00235069 Functional Category Investigative Drug with Natural Product
Superfamily Bacterial outer membrane Inhibitor Polymyxin B Superfamily
Class Class 607

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Oxytocin receptor Ligand Oxytocin Family 30 182
Penicillin binding protein inhibitor β-lactam aminopenicillin ... 12 359
Glucan synthesis regulatory protein Inhibitor Caspofungin Family 17 71
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 16 374
Angiotensin-converting enzyme inhibitor Phosphonate-containing... 7 41
Angiotensin-converting enzyme Inhibitor Quinapril Family 3 105
Angiotensin-converting enzyme Inhibitor Spirapril Family 17 86
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 7 54
ATP-sensitive inward rectifier potassium channel 10 Ligand Nat... 3 233
Growth hormone-releasing hormone receptor ligand polypeptide ... 14 34
Mu-type opioid receptor Ligand Alvimopan Family 32 325
Atrial natriuretic peptide receptor 1 Ligand Nesiritide Family 6 111
Bacterial outer membrane Inhibitor Polymyxin B Family 17 181
20S proteasome Inhibitor Carfilzomib Family 5 17
Angiotensin-converting enzyme Inhibitor Temocapril Family 4 15
Thymopentin family 20 133
Puromycin-sensitive aminopeptidase Inhibitor CHR-2797 Family 1 2
Angiotensin-converting enzyme and Neprilysin Inhibitor M100,24... 18 60
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
Dopamine reuptake Inhibitor Amineptine Family 2 5
Kappa-type opioid receptor Ligand Asimadoline Family 14 54
Thymosin Beta-4 family 8 30
Plitidepsin family 15 5
Ezatiostat family 1 4
Melanocortin receptor 4 Ligand Ro-27-3225 Family 6 52
Histone deacetylase 1 Inhibitor Chlamydocin Family 2 1
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
Flovagatran family 12 546
B1 bradykinin receptor Ligand B-9858 Family 4 14
Integrin alpha-V and Integrin beta-3 Inhibitor C[rgd-(s)-alpha... 19 95
Renin Inhibitor CP-80794 Family 16 112
Prothrombin Inhibitor Efegatran Family 9 47
Neprilysin Inhibitor Thiorphan Family 41 68
Vasopeptidase Inhibitor Sampatrilat Family 25 9
Neuromedin-K receptor Ligand Senktide Family 15 22
Proto-oncogene tyrosine-protein kinase Src Inhibitor RU83876 F... 3 51
Cathepsin F and Cruzipain Inhibitor Benzoyl-arginine-alanine-m... 49 348
Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131
Cruzipain Inhibitor WRR-204 Family 18 35
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Beta-secretase 1 Inhibitor MMI-175 Family 30 137
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Farnesyltransferase beta subunit, putative and Protein farnesy... 24 82
Plasmepsin-1 and Plasmepsin-2 Inhibitor PS-777621 Family 11 13
Disintegrin and metalloproteinase domain-containing protein 17... 8 7
Plasmepsin-2 Inhibitor PS-222036 Family 12 134
Integrin beta-3 Inhibitor RWJ-53419 Family 6 65
Somatostatin receptor type 1 Ligand Des-aa1,2,5-[(nalphame)lys... 16 11
Cathepsin B and Cathepsin K Inhibitor Z-ala-leu-lle-agly-ile-v... 17 7
Cathepsin B and Cathepsin K Inhibitor Z-ala-leu-nal-agly-ile-v... 3 2
Neuromedin-K receptor Ligand PD-160946 Family 10 32
Nociceptin receptor Ligand Fggftgcrkscrk Family 10 0
Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Beta-secretase 1 Inhibitor Glu-leu-asp-leu-(choh-ch2)-ala-ala-... 15 11
Calcitonin gene-related peptide type 1 receptor Ligand Fvptdvg... 8 8
Caspase-1 Inhibitor Z-vad-cho Family 8 34
Cathepsin B and Cathepsin K Inhibitor (s)-1-benzylcyclopentyl ... 11 5
Cathepsin B and Cathepsin S Inhibitor Cbz-ile-leu-ala-leuvsme ... 12 14
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Proto-oncogene tyrosine-protein kinase Src Inhibitor Ac-cys-il... 36 12
Beta-secretase 1 and Cathepsin D Inhibitor GRL-7234 Family 17 148
Plasmepsin-2 Inhibitor KNI-10232 Family 8 36
Beta-secretase 1 Inhibitor KMI-172 Family 3 0
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 6 24
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 3 21
Delta-type opioid receptor Ligand H-cxp-ala-gly-phe-leu-oh Family 1 8
Chymase Inhibitor Chymostatin Family 2 3
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor Azum... 3 10
Disks large homolog 4 Inhibitor N-(3,4-difluorophenyl)propyl-e... 3 0
Substance-P receptor Ligand [sar9,met(o2)11]-sp Family 34 9
Cytosolic phospholipase A2 Inhibitor Methyl 2-(2-oxo-8-phenylo... 2 3
Integrin alpha-V Inhibitor C[rgdf-(3s)-carboxymorpholine] Family 10 2
Caspase-4 and Cathepsin D Inhibitor Grassystatin A Family 24 6
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-154957 Family 2 3
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Inhibit... 5 23
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Receptor-type tyrosine-protein phosphatase C Ligand Asp-brpmp-... 2 0
Endothelin-converting enzyme 1 Inhibitor PO3 2-leu-nal-o-3k Fa... 3 26
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 49 19
Mu-type opioid receptor Ligand H-tyr-d-ala-aic-asp-val-val-gly... 48 8
Protein farnesyltransferase subunit beta Inhibitor L-739750 Fa... 4 0
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 12 8
Genome polyprotein Inhibitor Acasp-glu-dif-glu-cha-cys Family 13 17
Genome polyprotein Inhibitor Acasp-glu-met-glu-cha-cys Family 3 6
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Genome polyprotein Inhibitor Acasp-glu-cha-val-prb-cys Family 13 18
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 152 36
Sodium-dependent dopamine transporter Inhibitor Bip-tyr-thr-pr... 8 2
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 95 46
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Mu-type opioid receptor and Nociceptin receptor Ligand Nocicep... 35 5
Aminopeptidase N Inhibitor 2-cinnamamido-n4-hexyl-n1-hydroxysu... 24 8
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
Serine/threonine protein phosphatase PP1-alpha 1 catalytic sub... 10 0
Gamma-secretase subunit APH-1B and Presenilin-1 Inhibitor 3114... 8 9
Melanocortin receptor 4 and Melanocyte-stimulating hormone rec... 3 10
Pol polyprotein inhibitor 169168-45-0 family 7 11
Pol polyprotein inhibitor 169273-51-2 family 10 0
Pol polyprotein inhibitor AC1LA3TO family 8 0
Renin inhibitor (2S,4S,5S)-N-butyl-6-cyclohexyl-4-hydroxy-5-[[... 12 1
Renin inhibitor (2S,4S,5S)-N-(4-aminobutyl)-6-cyclohexyl-4-hyd... 32 2
Renin inhibitor benzyl N-[3-[[(2S,4S,5S)-6-cyclohexyl-4-hydrox... 2 0
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5R)-3-hydroxy-6... 40 29
Renin inhibitor (2S,4S,5S)-N-[3-[[amino-(cyanoamino)methyliden... 7 0
Pol polyprotein inhibitor penicillin deriv. 49 family 3 19
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5R)-3-hydroxy-6... 11 8
Renin inhibitor (2S,4S,5S)-6-cyclohexyl-4-hydroxy-5-[[(2S)-2-[... 1 0
Pol polyprotein inhibitor (2S)-2-[[2-(2,5-dioxoimidazolidin-4-... 2 0
Angiotensin-converting enzyme inhibitor (S)-1-((S)-5-benzamido... 5 2
Pol polyprotein inhibitor 180968-31-4 family 8 13
Pol polyprotein inhibitor benzyl N-[(2S,3R)-1-[[(2S,3R,4R)-4-(... 5 26
Pol polyprotein inhibitor AC1L9R8S family 5 4
Pol polyprotein inhibitor penicillin deriv. 69 family 1 1
Cathepsin D and Beta-secretase 1 inhibitor tert-butyl N-[(2S)-... 1 0
Cathepsin K inhibitor (4-phenylphenyl) (3S)-3-[[(3S)-1,2-dioxo... 4 10
Beta-secretase 1 and Cathepsin D inhibitor (1R,3S)-N-[(2S,3S)-... 2 25
Cathepsin S inhibitor ethyl 2-[[3-[[(2S)-3-cyclohexyl-2-[(1-me... 3 8
Cathepsin S inhibitor SureCN6857538 family 2 12
Cathepsin S inhibitor ethyl 2-[[3-[[(2S)-3-cyclohexyl-2-[(4-me... 2 9
Beta-secretase 1 inhibitor N-[(1S,2S)-3-(3,5-difluorophenyl)-1... 1 2
Pol polyprotein inhibitor benzyl N-[(2S)-1-[[(2S,3S,4R,5S)-3,4... 21 5
Tryptase alpha/beta-1 and Tryptase delta inhibitor (2S,3R)-3-[... 13 17
Neprilysin and Angiotensin-converting enzyme inhibitor AGN-PC-... 2 2
Renin and Cathepsin D inhibitor (2S)-N-[(2S,3R,4S)-1-cyclohexy... 13 2
Pol polyprotein inhibitor (2S)-4-benzyl-1-[(2S,4R)-4-benzyl-2-... 10 4
Neprilysin and Aminopeptidase N inhibitor (2S)-2-[[(2S)-2-[[[a... 13 1
Carboxypeptidase B and Carboxypeptidase B2 inhibitor (2S)-7-am... 3 9
Neprilysin and Aminopeptidase N inhibitor benzyl 2-[[(2S)-2-[[... 1 1
Renin inhibitor tert-butyl N-[1-[[(3S,6S,7R)-6-(cyclohexylmeth... 14 1
Angiotensin-converting enzyme inhibitor (2R)-1-[4-carboxy-4-(p... 3 3
NS3 and Non-structural protein 4A inhibitor (4S)-4-[[(2S)-3-ca... 1 1
Growth hormone secretagogue receptor type 1 ligand SureCN63170... 1 1
Caspase-1 inhibitor (3S)-3-[[(2S)-4-(2-naphthalen-1-ylethylami... 1 0
Caspase-1 inhibitor (3S)-5-(3,3-diphenylpropanoyloxy)-3-[[(2S)... 3 6
Caspase-1 inhibitor (3S)-5-[[(3aS,7aS)-2-oxo-3a,4,5,6,7,7a-hex... 3 0
Baculoviral IAP repeat-containing protein 2 and Baculoviral IA... 2 2
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 6 1
Cathepsin B and Calpain-2 catalytic subunit inhibitor AGN-PC-0... 2 2
Calpain-2 catalytic subunit and Calpain-1 catalytic subunit in... 1 8
Cathepsin B and Calpain-1 catalytic subunit inhibitor AGN-PC-0... 3 1
Renin and Cathepsin D inhibitor (3S)-4-[[6-acetamido-2-[[3-nap... 6 26
Pol polyprotein inhibitor Lysine Sulfonamide 11c family 3 73
Angiotensin-converting enzyme inhibitor SureCN9749318 family 2 0
Renin inhibitor [(2R)-1-[[(2S,3S,5R)-6-(butylamino)-1-cyclohex... 5 4
Endothelin-converting enzyme 1 and Neprilysin inhibitor (2S)-2... 1 8
Neprilysin inhibitor SureCN489232 family 3 9
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R)-5-phenyl... 4 1
Pol polyprotein inhibitor benzyl N-[(2S,3R)-4-[(3aR,6S,7aS)-6-... 3 2
Tyrosine--tRNA ligase, cytoplasmic inhibitor (2S)-2-[[(2S)-2-a... 5 2
Cathepsin K inhibitor [(3R)-4,4-dimethyl-1-phenylpentan-3-yl] ... 7 7
Neprilysin inhibitor (2S)-2-methyl-3-oxo-3-[[(2S)-1-phenyl-3-s... 5 2
Neutrophil collagenase and Matrix metalloproteinase-9 inhibito... 6 1
Growth factor receptor-bound protein 2 ligand 2-[(9S,10S,11E,1... 5 14
Chymase and Chymotrypsinogen A inhibitor tert-butyl N-[(2S)-1-... 2 7
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-cycl... 1 6
Renin and Cathepsin D inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-... 3 4
Tryptase alpha/beta-1 inhibitor methyl 3-[3-(aminomethyl)pheny... 1 3
Pol polyprotein inhibitor Sulfone deriv. 31 family 15 4
Growth factor receptor-bound protein 2 ligand [4-[[(2S,5S,9S,1... 2 1
Renin and Cathepsin D inhibitor (4S)-5-cyclohexyl-2,2-difluoro... 16 1
Pol polyprotein inhibitor AC1LADQG family 7 1
Pol polyprotein inhibitor methyl (2S)-2-[[(2S,3R)-2-[[1-[(2R,3... 1 0
Endothelin-converting enzyme 1 and Cathepsin D inhibitor N-[(2... 6 2
Pol polyprotein inhibitor 3-[[(3S,5R)-5-benzyl-1-[(2S,4R)-4-be... 4 0
Pol polyprotein inhibitor AC1LADII family 12 1
Beta-secretase 1 inhibitor (2S)-2-[(3S)-3-acetamido-3-butan-2-... 3 3
Beta-secretase 1 inhibitor (2S)-2-[(3R)-3-acetamido-3-(2-methy... 3 0
Beta-secretase 1 inhibitor (2S)-2-[(3S)-3-acetamido-3-butan-2-... 6 11
Beta-secretase 1 inhibitor (2S)-2-[(3S)-3-acetamido-3-butan-2-... 4 6
Pol polyprotein inhibitor SureCN3530080 family 3 8
NS3 inhibitor SureCN14450642 family 4 7
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5R)-5-benzyl-3-... 3 0
Pol polyprotein inhibitor L-689,502 family 17 2
Growth hormone-releasing hormone receptor ligand ethyl (1S)-1'... 4 7
Pol polyprotein inhibitor benzyl N-[(2S)-4-amino-1-[[(2S,3R)-4... 2 1
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 13 3
Renin inhibitor N-[(3S)-5-[2-(2-aminoethyl)morpholin-4-yl]-1-c... 4 2
Beta-secretase 1 and Cathepsin B inhibitor SureCN4666465 family 9 4
Proteasome subunit beta type-5 and Proteasome subunit beta typ... 1 0
Renin inhibitor AGN-PC-076HPD family 1 0
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 5 3
Beta-secretase 1 inhibitor 1-N-[(1R,2S)-1-[(2R,4S)-4-butoxypip... 5 1
Beta-secretase 1 and Cathepsin D inhibitor (4S)-N-[(2S,3R)-4-[... 3 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-2-... 6 0
Renin inhibitor 2-hydroxy-3-[[(4S,7S)-5-hydroxy-2,8-dimethyl-7... 1 0
Pol polyprotein inhibitor SDZ PRI 053 family 8 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 4 4
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2S,4R)... 5 8
Cathepsin E and Renin inhibitor (2S)-N-[2-[[(2S,3S,5S)-1-cyclo... 4 0
Beta-secretase 1 and Cathepsin B inhibitor 3-chloro-N-[(2S)-1-... 2 0
Renin and Cathepsin D inhibitor (4S)-5-cyclohexyl-2,2-difluoro... 15 0
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5S)-3-hydroxy-5... 4 12
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 1 3
Renin and Cathepsin D inhibitor (4S)-5-cyclohexyl-2,2-difluoro... 2 0
Renin and Cathepsin D inhibitor ethyl (4S)-5-cyclohexyl-2,2-di... 2 0
Angiotensin-converting enzyme inhibitor (2S,4R)-1-[(2S)-6-amin... 3 1
Renin and Cathepsin D inhibitor N-[(2S)-1-[[(2S)-1-[[(2S)-1-cy... 2 0
Renin inhibitor (1R,2R,3S)-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl... 5 0
Pol polyprotein inhibitor AC1LAJML family 4 0
Pol polyprotein inhibitor AC1LAH8S family 11 1
Pol polyprotein inhibitor [(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydr... 4 15
Type-2 angiotensin II receptor ligand SureCN3515167 family 2 0
Pol polyprotein inhibitor AC1NS2O6 family 3 0
Neprilysin inhibitor SureCN7437961 family 2 6
Pol polyprotein inhibitor AC1L9R8I family 1 0
Pol polyprotein inhibitor AC1L9R8M family 4 1
Pol polyprotein inhibitor AC1LA4ZN family 1 1
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 10 0
Renin inhibitor 2-methylpropyl N-[1-[[1-[[(3R,4S)-1-cyclohexyl... 14 0
Renin inhibitor tert-butyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3-h... 2 0
Pol polyprotein inhibitor AC1LA3C0 family 2 18
Renin and Cathepsin E inhibitor (2S)-N-[(2S,3S,5R)-1-cyclohexy... 1 0
Pol polyprotein inhibitor 4-benzyl-N-[(2S)-1-[[(2S,3R,4S,5S)-5... 3 0
Matrix metalloproteinase-9 and Interstitial collagenase inhibi... 1 0
Pol polyprotein inhibitor Diol-Based HIV-1 protease inhibitor ... 1 0
Pepsin A and Renin inhibitor N-[(3R)-1-[[(1S)-1-hydroxy-3-[[(2... 1 0
Pol polyprotein inhibitor (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5... 2 0
Renin inhibitor N-[(2S)-1-[[(2R)-1-[[(2S)-3-cyclohexyl-1-dimet... 3 1
Chymase and Chymotrypsinogen B inhibitor AGN-PC-075LTI family 2 3
Sigma non-opioid intracellular receptor 1 ligand tert-butyl N-... 1 9
Pol polyprotein inhibitor AC1LACBC family 2 0
Matrix metalloproteinase-9 and Stromelysin-1 inhibitor (2R,3R)... 1 0
Serine/threonine-protein kinase mTOR and Peptidyl-prolyl cis-t... 1 0
Angiotensin-converting enzyme and Neprilysin inhibitor (5R,7S)... 1 0
Histone deacetylase 1 and Histone deacetylase 8 inhibitor meth... 1 3
Renin inhibitor ethyl N-[1-[[1-[[(2S,3R,4S)-1-cyclohexyl-3,4-d... 2 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor (3R)-3-... 3 2
Neprilysin inhibitor AGN-PC-075S5F family 1 1
Angiotensin-converting enzyme inhibitor SureCN7263641 family 2 11
Calpain-1 catalytic subunit inhibitor Peptidyl alpha-Ketoacid,... 1 0
Renin inhibitor (2S)-2-[(2S)-1-(azetidin-1-yl)-1-oxo-3-phenylp... 1 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 2
Growth hormone-releasing hormone receptor ligand (1S)-1'-[(2R)... 7 4
Cathepsin D and Beta-secretase 1 inhibitor benzyl 3-[[(2R,3S)-... 1 0
Pol polyprotein inhibitor (2R,4S)-2-benzyl-5-[2-(tert-butylsul... 1 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 6
Pol polyprotein and Pepsin A inhibitor cgp 53820 family 1 1
Pol polyprotein inhibitor methyl (2S)-2-[[(2R,4S,5S)-2-benzyl-... 1 1
Ribonucleoside-diphosphate reductase large subunit and Ribonuc... 1 0
Tissue alpha-L-fucosidase inhibitor AGN-PC-074YKC family 1 0
Renin inhibitor MRM-HFA-CYM-CPY family 1 0
Gamma-secretase subunit PEN-2 inhibitor SureCN5966881 family 1 9
Beta-secretase 1 inhibitor 3-[[[(2S)-2-[[(3S,4S)-3-hydroxy-6-m... 2 4
Histone deacetylase 8 and Histone deacetylase 1 inhibitor tert... 1 0
Breast cancer type 1 susceptibility protein inhibitor (2S)-2-[... 1 0
Beta-secretase 1 inhibitor (2R)-4-amino-2-[[(2S)-2-[[(2S)-2-[[... 2 1
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 1 0
Bifunctional epoxide hydrolase 2 inhibitor (2S)-3-(3a,7a-dihyd... 1 0
Acetylcholinesterase and Cholinesterase inhibitor hexyl (2S)-5... 1 7
Pol polyprotein inhibitor methyl (2S)-2-[[(2S)-2-[[(2S)-2-[5-[... 1 2
Gag-Pro polyprotein inhibitor (4S)-3-[(2S,3S)-3-[[(2S,3S)-2-[[... 4 0
Angiotensin-converting enzyme and Angiotensin-converting enzym... 1 0
Kinesin-like protein KIF11 inhibitor methyl (2S)-2-[[(2R)-2-am... 1 1
Pol polyprotein inhibitor Aminodiol OH-FuranCONH deriv. family 1 0
Calpain-1 catalytic subunit inhibitor Peptidyl alpha-Ketoester... 1 0
Pol polyprotein inhibitor AC1LA6OP family 2 0
Putative NP ZINC35361895 Family 12 0
NP (2s)-2-(2-((tert-butoxycarbonyl)amino)-3-phenylpropanamido)... 2 0
Putative NP ZINC12898297 Family 2 0
Putative NP ZINC08790318 Family 1 0
4-[[[1-[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-pheny... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00235020 CHEMBL74109 Bioactive ethyl N-[1-[[1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235059 CHEMBL431999 Bioactive AC1NUI15
CFAMM00234911 CHEMBL352523 Bioactive methyl (3S)-4-cyclohexyl-2-hydroxy-3-[[4-methyl-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]amino]pentanoyl]amino]butanoate
CFAMM00235026 CHEMBL21266 Bioactive tert-butyl N-[(2S,3S,5R)-6-[[1-[(1-amino-1-oxo-3-phenylpropan-2-yl)amino]-4-methyl-1-oxopentan-2-yl]amino]-5-benzyl-3-hydroxy-6-oxo-1-phenylhexan-2-yl]carbamate
CFAMM00235085 CHEMBL290900 Bioactive AC1LAJHJ
CFAMM00234979 CHEMBL2112610 Bioactive tert-butyl N-[(2S,3R,5R)-5-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(2-methylpropylcarbamoyl)hex-5-en-2-yl]carbamoyl]-3-hydroxy-1-phenyldec-9-en-2-yl]carbamate
CFAMM00235039 CHEMBL300711 Bioactive 2-(dimethylamino)ethyl N-[(3S,5S,6S)-7-cyclohexyl-5-hydroxy-6-[[(2S)-2-[[(2S)-1-[4-(methoxymethoxy)piperidin-1-yl]-1-oxo-3-phenylpropan-2-yl]amino]hexanoyl]amino]-2-methylheptan-3-yl]carbamate
CFAMM00235052 CHEMBL344155 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(1S,2S)-3-cyclohexyl-1-dimethoxyphosphoryl-1-hydroxypropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235124 CHEMBL295736 Bioactive AGN-PC-073NZ0
CFAMM00235150 CHEMBL97299 Bioactive L-682, 679 analog 31
CFAMM00234931 CHEMBL122803 Bioactive tert-butyl N-[(2S)-5-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(2-methylpropylcarbamoyl)hex-5-en-2-yl]carbamoyl]-3-hydroxy-1-phenylnonan-2-yl]carbamate
CFAMM00235091 CHEMBL281439 Bioactive AC1L9TAW
CFAMM00235104 CHEMBL307047 Bioactive tert-butyl N-[1-[[1-[[(3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00234897 CHEMBL85625 Bioactive AGN-PC-074LEF
CFAMM00234958 CHEMBL95413 Bioactive AC1NUI12
CFAMM00235071 CHEMBL21088 Bioactive tert-butyl N-[(E,2S,3S,5R)-5-[[1-[(1-amino-1-oxo-3-phenylpropan-2-yl)amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]-3-hydroxy-1,8-diphenyloct-7-en-2-yl]carbamate
CFAMM00234998 CHEMBL291139 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-1-oxopent-4-en-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235011 CHEMBL123941 Bioactive tert-butyl N-[(2S,3R,5R)-5-[[(2S,3S,4R)-1-cyclohexyl-3-hydroxy-4-(hydroxymethyl)-6-methylheptan-2-yl]carbamoyl]-3-hydroxy-7-methyl-1-phenyloctan-2-yl]carbamate
CFAMM00235084 CHEMBL97362 Bioactive AC1NUI1K
CFAMM00235097 CHEMBL364773 Bioactive tert-butyl N-[(3S,5R)-6-[(1-amino-3-methyl-1-oxobutan-2-yl)amino]-5-benzyl-3-hydroxy-6-oxo-1-phenylhexan-2-yl]carbamate
CFAMM00234937 CHEMBL94266 Bioactive AC1NUHZZ
CFAMM00234950 CHEMBL331085 Bioactive tert-butyl N-[1-[[(3S,6S,7R)-6-(cyclohexylmethyl)-7-hydroxy-10-(2-methylpropyl)-4,8,13-trioxo-1,9-dioxa-5-azacyclotridec-3-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235038 CHEMBL386563 Bioactive 1zsr
CFAMM00235051 CHEMBL308858 Bioactive tert-butyl N-[1-[[1-[[(3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-methylsulfanyl-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00234943 CHEMBL318700 Bioactive AC1NUI1E
CFAMM00235017 CHEMBL95419 Bioactive AC1NUHZT
CFAMM00235077 CHEMBL433024 Bioactive tert-butyl N-[(2S)-1-[[1-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(2-methylpropylcarbamoyl)hex-5-en-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235103 CHEMBL262300 Bioactive tert-butyl N-[(2S,3S,5R)-6-[[(2S)-1-[(2-amino-3-phenylpropanoyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-5-benzyl-3-hydroxy-6-oxo-1-phenylhexan-2-yl]carbamate
CFAMM00235116 CHEMBL306603 Bioactive ethyl N-[1-[[1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-naphthalen-1-yl-1-oxopropan-2-yl]carbamate
CFAMM00235129 CHEMBL305463 Bioactive (3S)-N-tert-butyl-2-[(2R,3S)-3-[[(2S)-2-(heptanoylamino)-3-methylbutanoyl]amino]-2-hydroxy-4-phenylbutyl]-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinoline-3-carboxamide
CFAMM00234909 CHEMBL444057 Bioactive tert-butyl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-6-[[(1S,5R)-5-hydroxycyclopent-2-en-1-yl]amino]-6-oxo-1-phenylhexan-2-yl]carbamate
CFAMM00234922 CHEMBL291195 Bioactive AC1NUI38
CFAMM00235083 CHEMBL95516 Bioactive AC1NUI1N
CFAMM00235096 CHEMBL428854 Bioactive AGN-PC-037TW8
CFAMM00234936 CHEMBL72210 Bioactive tert-butyl N-[1-[[1-[[(3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00234949 CHEMBL98284 Bioactive AC1NUI0W
CFAMM00235037 CHEMBL98129 Bioactive AC1NUI0Z
CFAMM00235050 CHEMBL308859 Bioactive tert-butyl N-[1-[[1-[[(3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235122 CHEMBL99412 Bioactive 126409-30-1
CFAMM00235135 CHEMBL289195 Bioactive L-682,679
CFAMM00235076 CHEMBL273402 Bioactive 2-acetamido-N-[1-[[(2S,4S)-4-[[2-[(2-acetamido-3-methylbutanoyl)amino]-3-methylbutanoyl]amino]-3-hydroxy-1,5-diphenylpentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-3-methylbutanamide
CFAMM00235089 CHEMBL305230 Bioactive tert-butyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3-hydroxy-4-propan-2-ylsulfanylbutan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235043 CHEMBL97253 Bioactive AC1NUI1Q
CFAMM00235102 CHEMBL2111809 Bioactive tert-butyl N-[(2S,3R,5S)-5-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(2-methylpropylcarbamoyl)hex-5-en-2-yl]carbamoyl]-3-hydroxy-1-phenyldec-9-en-2-yl]carbamate
CFAMM00235115 CHEMBL60653 Bioactive tert-butyl N-[1-[[1-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(3-methylbutylcarbamoyl)hex-5-en-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235023 CHEMBL98229 Bioactive AC1NUI1T
CFAMM00234914 CHEMBL369416 Bioactive WPE-III-31C
CFAMM00234976 CHEMBL417905 Bioactive 2-morpholin-4-ylethyl N-[(3S,5S,6S)-7-cyclohexyl-5-hydroxy-6-[[(2S)-2-[[(2S)-1-[4-(methoxymethoxy)piperidin-1-yl]-1-oxo-3-phenylpropan-2-yl]amino]hexanoyl]amino]-2-methylheptan-3-yl]carbamate
CFAMM00235049 CHEMBL311504 Bioactive tert-butyl N-[(2R)-1-[[1-[[(3S)-3-hydroxy-5-[[1-(3-methylbutylamino)-1-oxopropan-2-yl]amino]-5-oxo-1-phenylpentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate
CFAMM00235015 CHEMBL263978 Bioactive 1izh
CFAMM00235055 CHEMBL99016 Bioactive AC1NUI08
CFAMM00235114 CHEMBL60654 Bioactive tert-butyl N-[1-[[1-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(2-methylpropylcarbamoyl)hex-5-en-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00234907 CHEMBL340907 Bioactive tert-butyl N-[(2S)-1-[[1-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(2-methylpropylcarbamoyl)hex-5-en-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00234954 CHEMBL72185 Bioactive tert-butyl N-[1-[[1-[[(3S)-1-cyclohexyl-3-hydroxy-6-methylheptan-2-yl]amino]-3-(4H-imidazol-4-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00234969 CHEMBL307814 Bioactive ethyl N-[1-[[1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-iodophenyl)-1-oxopropan-2-yl]carbamate
CFAMM00235068 CHEMBL96996 Bioactive AC1NUI1Z
CFAMM00235081 CHEMBL348469 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3R)-1-cyclohexyl-3-hydroxy-4-propan-2-ylsulfanylbutan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00234920 CHEMBL222915 Bioactive methyl (2S)-2-[[(2S)-2-[[benzyl-[(2R,3R)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-phenylbutyl]carbamoyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoate
CFAMM00234975 CHEMBL95116 Bioactive AC1NUI1W
CFAMM00235061 CHEMBL83600 Bioactive (3S)-3-hydroxy-N-[1-(3-methylbutylamino)-1-oxopropan-2-yl]-4-[[3-methyl-2-[[(2R)-3-methyl-2-(3-methylbutanoylamino)butanoyl]amino]butanoyl]amino]-5-phenylpentanamide
CFAMM00235133 CHEMBL297929 Bioactive ethyl N-[(2S)-1-[[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-iodophenyl)-1-oxopropan-2-yl]carbamate
CFAMM00235100 CHEMBL88255 Bioactive (2R)-2-acetamido-N-[(2R)-1-[[(2S,4S)-4-[[(2S)-2-[[(2S)-2-acetamido-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxy-1,5-diphenylpentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-3-methylbutanamide
CFAMM00234927 CHEMBL73717 Bioactive ethyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3,4-dihydroxyhexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235001 CHEMBL48537 Bioactive (2S)-N-[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]-2-[[(2S)-1-[4-(methoxymethoxy)piperidin-1-yl]-1-oxo-3-phenylpropan-2-yl]amino]hexanamide
CFAMM00235028 CHEMBL308356 Bioactive ethyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235087 CHEMBL58522 Bioactive AC1NUI1H
CFAMM00234893 CHEMBL283583 Bioactive Hydroxyethylene deriv. 11
CFAMM00235080 CHEMBL97847 Bioactive AC1NUI02
CFAMM00234919 CHEMBL45953 Bioactive AC1L9R8H
CFAMM00234933 CHEMBL59972 Bioactive tert-butyl N-[1-[[1-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(3-methylbutylcarbamoyl)hex-5-en-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235021 CHEMBL100310 Bioactive AC1NUI18
CFAMM00235034 CHEMBL345888 Bioactive methyl (2S)-2-[[(2S)-2-[[4-[[(2S)-2-[[2-[[(2S)-2-amino-3-phenylpropanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-3-hydroxy-6-methylheptanoyl]amino]propanoyl]amino]-3-phenylpropanoate
CFAMM00235093 CHEMBL323203 Bioactive methyl N-[(2S)-1-[[(2S,3R)-4-[[[(2S)-2-acetamido-3-methylbutanoyl]amino]-(cyclohexylmethyl)amino]-3-hydroxy-1-phenylbutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate
CFAMM00235106 CHEMBL1790766 Bioactive tert-butyl N-[(2S,3S,5R)-6-[[(2S,3S)-1-[(2-amino-3-phenylpropanoyl)amino]-3-methyl-1-oxopentan-2-yl]amino]-5-benzyl-3-hydroxy-6-oxo-1-phenylhexan-2-yl]carbamate
CFAMM00234926 CHEMBL122234 Bioactive tert-butyl N-[(2S)-1-[[1-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(2-methylpropylcarbamoyl)hex-5-en-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235047 CHEMBL47480 Bioactive Boc-PPE-Leu-Phe-NH2
CFAMM00235073 CHEMBL298788 Bioactive AC1L9R8J
CFAMM00235119 CHEMBL165580 Bioactive (2S,4S,5S)-5-[[(2S)-2-[(2-acetamido-3-phenylpropanoyl)amino]hexanoyl]amino]-N-butyl-6-cyclohexyl-4-hydroxy-2-propan-2-ylhexanamide
CFAMM00235013 CHEMBL84879 Bioactive AGN-PC-074LDK
CFAMM00235086 CHEMBL421019 Bioactive tert-butyl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-6-[[(1R,5R)-5-hydroxycyclopent-2-en-1-yl]amino]-6-oxo-1-phenylhexan-2-yl]carbamate
CFAMM00234892 CHEMBL310447 Bioactive ethyl (2R,3S)-4-cyclohexyl-2-hydroxy-3-[[(2S)-4-methyl-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]amino]pentanoyl]amino]butanoate
CFAMM00235138 CHEMBL68320 Bioactive tert-butyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3-hydroxy-4-propan-2-ylsulfonylbutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235151 CHEMBL166771 Bioactive tert-butyl N-[1-[[(2S)-1-[[(2S,3S,5S)-5-(butylcarbamoyl)-1-cyclohexyl-3-hydroxy-6-methylheptan-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235066 CHEMBL52868 Bioactive tert-butyl (3R,4S,6R)-7-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3,6-dibenzyl-4-hydroxy-7-oxoheptanoate
CFAMM00235069 DNC004081 Investigative Drug SC-5003

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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