CFAM

Seed Molecules
Non-seed Members

CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00235020 CHEMBL74109 Bioactive ethyl N-[1-[[1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235059 CHEMBL431999 Bioactive AC1NUI15
CFAMM00234911 CHEMBL352523 Bioactive methyl (3S)-4-cyclohexyl-2-hydroxy-3-[[4-methyl-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]amino]pentanoyl]amino]butanoate
CFAMM00235026 CHEMBL21266 Bioactive tert-butyl N-[(2S,3S,5R)-6-[[1-[(1-amino-1-oxo-3-phenylpropan-2-yl)amino]-4-methyl-1-oxopentan-2-yl]amino]-5-benzyl-3-hydroxy-6-oxo-1-phenylhexan-2-yl]carbamate
CFAMM00235085 CHEMBL290900 Bioactive AC1LAJHJ
CFAMM00234979 CHEMBL2112610 Bioactive tert-butyl N-[(2S,3R,5R)-5-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(2-methylpropylcarbamoyl)hex-5-en-2-yl]carbamoyl]-3-hydroxy-1-phenyldec-9-en-2-yl]carbamate
CFAMM00235039 CHEMBL300711 Bioactive 2-(dimethylamino)ethyl N-[(3S,5S,6S)-7-cyclohexyl-5-hydroxy-6-[[(2S)-2-[[(2S)-1-[4-(methoxymethoxy)piperidin-1-yl]-1-oxo-3-phenylpropan-2-yl]amino]hexanoyl]amino]-2-methylheptan-3-yl]carbamate
CFAMM00235052 CHEMBL344155 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(1S,2S)-3-cyclohexyl-1-dimethoxyphosphoryl-1-hydroxypropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235124 CHEMBL295736 Bioactive AGN-PC-073NZ0
CFAMM00235150 CHEMBL97299 Bioactive L-682, 679 analog 31
CFAMM00234931 CHEMBL122803 Bioactive tert-butyl N-[(2S)-5-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(2-methylpropylcarbamoyl)hex-5-en-2-yl]carbamoyl]-3-hydroxy-1-phenylnonan-2-yl]carbamate
CFAMM00235091 CHEMBL281439 Bioactive AC1L9TAW
CFAMM00235104 CHEMBL307047 Bioactive tert-butyl N-[1-[[1-[[(3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00234897 CHEMBL85625 Bioactive AGN-PC-074LEF
CFAMM00234958 CHEMBL95413 Bioactive AC1NUI12
CFAMM00235071 CHEMBL21088 Bioactive tert-butyl N-[(E,2S,3S,5R)-5-[[1-[(1-amino-1-oxo-3-phenylpropan-2-yl)amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]-3-hydroxy-1,8-diphenyloct-7-en-2-yl]carbamate
CFAMM00234998 CHEMBL291139 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-1-oxopent-4-en-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235011 CHEMBL123941 Bioactive tert-butyl N-[(2S,3R,5R)-5-[[(2S,3S,4R)-1-cyclohexyl-3-hydroxy-4-(hydroxymethyl)-6-methylheptan-2-yl]carbamoyl]-3-hydroxy-7-methyl-1-phenyloctan-2-yl]carbamate
CFAMM00235084 CHEMBL97362 Bioactive AC1NUI1K
CFAMM00235097 CHEMBL364773 Bioactive tert-butyl N-[(3S,5R)-6-[(1-amino-3-methyl-1-oxobutan-2-yl)amino]-5-benzyl-3-hydroxy-6-oxo-1-phenylhexan-2-yl]carbamate
CFAMM00234937 CHEMBL94266 Bioactive AC1NUHZZ
CFAMM00234950 CHEMBL331085 Bioactive tert-butyl N-[1-[[(3S,6S,7R)-6-(cyclohexylmethyl)-7-hydroxy-10-(2-methylpropyl)-4,8,13-trioxo-1,9-dioxa-5-azacyclotridec-3-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235038 CHEMBL386563 Bioactive 1zsr
CFAMM00235051 CHEMBL308858 Bioactive tert-butyl N-[1-[[1-[[(3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-methylsulfanyl-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00234943 CHEMBL318700 Bioactive AC1NUI1E
CFAMM00235017 CHEMBL95419 Bioactive AC1NUHZT
CFAMM00235077 CHEMBL433024 Bioactive tert-butyl N-[(2S)-1-[[1-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(2-methylpropylcarbamoyl)hex-5-en-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235103 CHEMBL262300 Bioactive tert-butyl N-[(2S,3S,5R)-6-[[(2S)-1-[(2-amino-3-phenylpropanoyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-5-benzyl-3-hydroxy-6-oxo-1-phenylhexan-2-yl]carbamate
CFAMM00235116 CHEMBL306603 Bioactive ethyl N-[1-[[1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-naphthalen-1-yl-1-oxopropan-2-yl]carbamate
CFAMM00235129 CHEMBL305463 Bioactive (3S)-N-tert-butyl-2-[(2R,3S)-3-[[(2S)-2-(heptanoylamino)-3-methylbutanoyl]amino]-2-hydroxy-4-phenylbutyl]-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinoline-3-carboxamide
CFAMM00234909 CHEMBL444057 Bioactive tert-butyl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-6-[[(1S,5R)-5-hydroxycyclopent-2-en-1-yl]amino]-6-oxo-1-phenylhexan-2-yl]carbamate
CFAMM00234922 CHEMBL291195 Bioactive AC1NUI38
CFAMM00235083 CHEMBL95516 Bioactive AC1NUI1N
CFAMM00235096 CHEMBL428854 Bioactive AGN-PC-037TW8
CFAMM00234936 CHEMBL72210 Bioactive tert-butyl N-[1-[[1-[[(3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00234949 CHEMBL98284 Bioactive AC1NUI0W
CFAMM00235037 CHEMBL98129 Bioactive AC1NUI0Z
CFAMM00235050 CHEMBL308859 Bioactive tert-butyl N-[1-[[1-[[(3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235122 CHEMBL99412 Bioactive 126409-30-1
CFAMM00235135 CHEMBL289195 Bioactive L-682,679
CFAMM00235076 CHEMBL273402 Bioactive 2-acetamido-N-[1-[[(2S,4S)-4-[[2-[(2-acetamido-3-methylbutanoyl)amino]-3-methylbutanoyl]amino]-3-hydroxy-1,5-diphenylpentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-3-methylbutanamide
CFAMM00235089 CHEMBL305230 Bioactive tert-butyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3-hydroxy-4-propan-2-ylsulfanylbutan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235043 CHEMBL97253 Bioactive AC1NUI1Q
CFAMM00235102 CHEMBL2111809 Bioactive tert-butyl N-[(2S,3R,5S)-5-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(2-methylpropylcarbamoyl)hex-5-en-2-yl]carbamoyl]-3-hydroxy-1-phenyldec-9-en-2-yl]carbamate
CFAMM00235115 CHEMBL60653 Bioactive tert-butyl N-[1-[[1-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(3-methylbutylcarbamoyl)hex-5-en-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235023 CHEMBL98229 Bioactive AC1NUI1T
CFAMM00234914 CHEMBL369416 Bioactive WPE-III-31C
CFAMM00234976 CHEMBL417905 Bioactive 2-morpholin-4-ylethyl N-[(3S,5S,6S)-7-cyclohexyl-5-hydroxy-6-[[(2S)-2-[[(2S)-1-[4-(methoxymethoxy)piperidin-1-yl]-1-oxo-3-phenylpropan-2-yl]amino]hexanoyl]amino]-2-methylheptan-3-yl]carbamate
CFAMM00235049 CHEMBL311504 Bioactive tert-butyl N-[(2R)-1-[[1-[[(3S)-3-hydroxy-5-[[1-(3-methylbutylamino)-1-oxopropan-2-yl]amino]-5-oxo-1-phenylpentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate
CFAMM00235015 CHEMBL263978 Bioactive 1izh
CFAMM00235055 CHEMBL99016 Bioactive AC1NUI08
CFAMM00235114 CHEMBL60654 Bioactive tert-butyl N-[1-[[1-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(2-methylpropylcarbamoyl)hex-5-en-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00234907 CHEMBL340907 Bioactive tert-butyl N-[(2S)-1-[[1-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(2-methylpropylcarbamoyl)hex-5-en-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00234954 CHEMBL72185 Bioactive tert-butyl N-[1-[[1-[[(3S)-1-cyclohexyl-3-hydroxy-6-methylheptan-2-yl]amino]-3-(4H-imidazol-4-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00234969 CHEMBL307814 Bioactive ethyl N-[1-[[1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-iodophenyl)-1-oxopropan-2-yl]carbamate
CFAMM00235068 CHEMBL96996 Bioactive AC1NUI1Z
CFAMM00235081 CHEMBL348469 Bioactive tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3R)-1-cyclohexyl-3-hydroxy-4-propan-2-ylsulfanylbutan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00234920 CHEMBL222915 Bioactive methyl (2S)-2-[[(2S)-2-[[benzyl-[(2R,3R)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-phenylbutyl]carbamoyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoate
CFAMM00234975 CHEMBL95116 Bioactive AC1NUI1W
CFAMM00235061 CHEMBL83600 Bioactive (3S)-3-hydroxy-N-[1-(3-methylbutylamino)-1-oxopropan-2-yl]-4-[[3-methyl-2-[[(2R)-3-methyl-2-(3-methylbutanoylamino)butanoyl]amino]butanoyl]amino]-5-phenylpentanamide
CFAMM00235133 CHEMBL297929 Bioactive ethyl N-[(2S)-1-[[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-iodophenyl)-1-oxopropan-2-yl]carbamate
CFAMM00235100 CHEMBL88255 Bioactive (2R)-2-acetamido-N-[(2R)-1-[[(2S,4S)-4-[[(2S)-2-[[(2S)-2-acetamido-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxy-1,5-diphenylpentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-3-methylbutanamide
CFAMM00234927 CHEMBL73717 Bioactive ethyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3,4-dihydroxyhexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235001 CHEMBL48537 Bioactive (2S)-N-[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]-2-[[(2S)-1-[4-(methoxymethoxy)piperidin-1-yl]-1-oxo-3-phenylpropan-2-yl]amino]hexanamide
CFAMM00235028 CHEMBL308356 Bioactive ethyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235087 CHEMBL58522 Bioactive AC1NUI1H
CFAMM00234893 CHEMBL283583 Bioactive Hydroxyethylene deriv. 11
CFAMM00235080 CHEMBL97847 Bioactive AC1NUI02
CFAMM00234919 CHEMBL45953 Bioactive AC1L9R8H
CFAMM00234933 CHEMBL59972 Bioactive tert-butyl N-[1-[[1-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(3-methylbutylcarbamoyl)hex-5-en-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235021 CHEMBL100310 Bioactive AC1NUI18
CFAMM00235034 CHEMBL345888 Bioactive methyl (2S)-2-[[(2S)-2-[[4-[[(2S)-2-[[2-[[(2S)-2-amino-3-phenylpropanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-3-hydroxy-6-methylheptanoyl]amino]propanoyl]amino]-3-phenylpropanoate
CFAMM00235093 CHEMBL323203 Bioactive methyl N-[(2S)-1-[[(2S,3R)-4-[[[(2S)-2-acetamido-3-methylbutanoyl]amino]-(cyclohexylmethyl)amino]-3-hydroxy-1-phenylbutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate
CFAMM00235106 CHEMBL1790766 Bioactive tert-butyl N-[(2S,3S,5R)-6-[[(2S,3S)-1-[(2-amino-3-phenylpropanoyl)amino]-3-methyl-1-oxopentan-2-yl]amino]-5-benzyl-3-hydroxy-6-oxo-1-phenylhexan-2-yl]carbamate
CFAMM00234926 CHEMBL122234 Bioactive tert-butyl N-[(2S)-1-[[1-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(2-methylpropylcarbamoyl)hex-5-en-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235047 CHEMBL47480 Bioactive Boc-PPE-Leu-Phe-NH2
CFAMM00235073 CHEMBL298788 Bioactive AC1L9R8J
CFAMM00235119 CHEMBL165580 Bioactive (2S,4S,5S)-5-[[(2S)-2-[(2-acetamido-3-phenylpropanoyl)amino]hexanoyl]amino]-N-butyl-6-cyclohexyl-4-hydroxy-2-propan-2-ylhexanamide
CFAMM00235013 CHEMBL84879 Bioactive AGN-PC-074LDK
CFAMM00235086 CHEMBL421019 Bioactive tert-butyl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-6-[[(1R,5R)-5-hydroxycyclopent-2-en-1-yl]amino]-6-oxo-1-phenylhexan-2-yl]carbamate
CFAMM00234892 CHEMBL310447 Bioactive ethyl (2R,3S)-4-cyclohexyl-2-hydroxy-3-[[(2S)-4-methyl-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]amino]pentanoyl]amino]butanoate
CFAMM00235138 CHEMBL68320 Bioactive tert-butyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3-hydroxy-4-propan-2-ylsulfonylbutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235151 CHEMBL166771 Bioactive tert-butyl N-[1-[[(2S)-1-[[(2S,3S,5S)-5-(butylcarbamoyl)-1-cyclohexyl-3-hydroxy-6-methylheptan-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CFAMM00235066 CHEMBL52868 Bioactive tert-butyl (3R,4S,6R)-7-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3,6-dibenzyl-4-hydroxy-7-oxoheptanoate
CFAMM00235069 DNC004081 Investigative Drug SC-5003

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by

2014.08.29