CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1302
Family Name Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-biphenyl-4-yl-heptanoic Acid Hydroxyamide Family
No. of Seeds 5 No. of Other Members 14
Family Centroid CFAMM00235173 Functional Category Investigative Drug with Human Metabolite
Superfamily Histone deacetylase 1 and Histone deacetylase 2 Binder Superfamily 2
Class Class 2057

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Sodium channel protein type 1 subunit alpha Ligand Phenacemide... 5 6
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
DNA Binder Procarbazine Family 8 358
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 2 9
Cytochrome P450 2D6 Inhibitor Glutethimide Family 1 1
Calcium-activated potassium channel subunit alpha-1 Ligand ICA... 14 14
C-X-C chemokine receptor type 1 and C-X-C chemokine receptor t... 5 30
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-4-isobutyl-ben... 4 43
Histone deacetylase Inhibitor CG-1521 Family 2 8
Chymase Inhibitor Phenylalanylmethane Family 1 8
Histone deacetylase 1 Inhibitor 8-(3-benzoyl-ureido)-octanoic ... 7 13
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 5-(4... 2 3
Angiopoietin-1 receptor and Cyclin-dependent kinase 1 Inhibito... 1 3
Cannabinoid receptor 1 Ligand N-(3,3-diphenyl)propyl-2-phenyla... 4 18
Histone deacetylase 2 Inhibitor N-hydroxy-e-3-(4'-cyanobipheny... 2 1
Histone deacetylase 1 Inhibitor N-hydroxy-6-oxo-6-phenylhexana... 7 7
Histone deacetylase 1 Inhibitor N-hydroxy-7-(naphthalen-2-yl)-... 3 2
Histone deacetylase 1 Inhibitor N-hydroxy-8-(naphthalen-2-yl)n... 6 3
Aminopeptidase N Inhibitor N1,2-dibenzyl-n3-hydroxymalonamide ... 5 23
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-n-methyl-2-nap... 3 3
Arachidonate 5-lipoxygenase Inhibitor Phenanthrene-3-carboxyli... 7 4
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-n-methyl-benza... 3 9
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-n-methyl-2,3,3... 1 0
Aminopeptidase N Inhibitor 2-benzyl-n1-hydroxy-n3-(4-phenylbut... 5 3
Collagenase 3 and Macrophage metalloelastase inhibitor N-hydro... 1 0
Botulinum neurotoxin type A inhibitor 2-[3-(4-bromophenyl)-1-a... 1 0
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 2 0
hexanamide NP 2-(3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)hexa... 8 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00235166 DNC011077 Investigative Drug 4-Phenylbutyrohydroxamic acid
CFAMM00235173 DNC004098 Investigative Drug 7-Biphenyl-4-yl-heptanoic acid hydroxyamide
CFAMM00235165 DNC009953 Investigative Drug N-hydroxy-2,2-diphenylacetamide
CFAMM00235155 DNC009766 Investigative Drug 5-(Biphenyl-4-yl)-pentanoic acid N-hydroxyamide
CFAMM00235160 DNC004084 Investigative Drug 8-Phenyl-octanoic acid hydroxyamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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