CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1309
Family Name Integrin beta-3 Inhibitor SKF-107260 Family
No. of Seeds 5 No. of Other Members 8
Family Centroid CFAMM00235193 Functional Category Investigative Drug
Superfamily Integrin beta-3 Inhibitor SKF-107260 Superfamily
Class Class 2034

Cousin Family NamesSeedsMembers
Integrin alpha-V and Integrin beta-3 Inhibitor C[rgd-(s)-alpha... 19 95
Neuromedin-K receptor Ligand Senktide Family 15 22
Integrin alpha-V and Integrin beta-3 Inhibitor Cyclo-[-arg-gly... 5 38
Integrin beta-3 Inhibitor DMP-728 Family 3 0
Integrin beta-3 Inhibitor SB-208651 Family 9 28
Integrin beta-3 Inhibitor Lotrafiban Family 5 1
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor Azum... 3 10
Substance-P receptor Ligand [sar9,met(o2)11]-sp Family 34 9
Integrin alpha-V Inhibitor C[rgdf-(3s)-carboxymorpholine] Family 10 2
Integrin beta-3 and Integrin alpha-V inhibitor 2-[(1R,5S,11S,1... 8 2
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R,6S,12S)-6... 7 0
Atrial natriuretic peptide receptor 1 and Atrial natriuretic p... 3 0
Integrin beta-3 and Integrin alpha-IIb inhibitor 2-[(4R,10R,13... 1 1
Prothrombin and Coagulation factor X inhibitor AC1NDIV9 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00235206 CHEMBL128299 Bioactive SKF-107260
CFAMM00235204 CHEMBL165459 Bioactive 2-[(4R,10R)-4-[3-(diaminomethylideneamino)propyl]-3-methyl-2,5,8,11-tetraoxo-15,16-dithia-3,6,9,12-tetrazabicyclo[15.4.0]henicosa-1(21),17,19-trien-10-yl]acetic acid
CFAMM00235203 CHEMBL165266 Bioactive CHEMBL165266
CFAMM00235202 CHEMBL132216 Bioactive (3S)-3-[[2-[[(2S)-5-(diaminomethylideneamino)-2-[methyl-(2-sulfanylbenzoyl)amino]pentanoyl]amino]acetyl]amino]-4-oxo-4-(2-sulfanylanilino)butanoic acid
CFAMM00235193 DNC004113 Investigative Drug SKF-107260

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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