CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1317
Family Name MO15-related protein kinase Pfmrk Inhibitor 3-[3-(2-hydroxy-ethoxy)-phenyl]-1h-quinolin-2-one Family
No. of Seeds 1 No. of Other Members 6
Family Centroid CFAMM00235565 Functional Category Investigative Drug with Natural Product
Superfamily MO15-related protein kinase Pfmrk and Glutamate receptor ionotropic, NMDA 2A Binder Superfamily
Class Class 2065

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Tranilast Family 5 125
Dihydroorotate dehydrogenase and Interleukin-17A Inhibitor Vid... 4 74
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
High affinity nerve growth factor receptor and RAF proto-oncog... 3 29
Cannabinoid receptor 1 Ligand N-(4-methoxyphenyl)oleamide Family 4 23
Liver carboxylesterase 1 Inhibitor 5-(trifluoromethoxy)-1h-ind... 3 12
Leukotriene A-4 hydrolase Inhibitor N5-[4-(2-oxo-3-phenylpropo... 1 61
Urotensin-2 receptor Ligand JNJ-28318706 Family 4 227
Proto-oncogene tyrosine-protein kinase receptor Ret Ligand (z)... 1 60
Amine oxidase [flavin-containing] A and Mitogen-activated prot... 1 71
Beta-ketoacyl-acyl carrier protein synthase III Inhibitor 2-(4... 2 6
Tubulin beta chain Inhibitor Gnf-pf-117 Family 2 16
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
Cyclic AMP-specific phosphodiesterase SSPDE4A1A inhibitor AGN-... 2 8
Major prion protein and Microtubule-associated protein tau inh... 2 10
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 3
Histone deacetylase 1 and Histone deacetylase 2 inhibitor 4-[3... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00235565 DNC004140 Investigative Drug 3-[3-(2-Hydroxy-ethoxy)-phenyl]-1H-quinolin-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27698 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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