CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1334
Family Name Acetylcholinesterase and Cholinesterase Inhibitor N,n'-(1',10'-decylene)-bis-(-)-nor-mep Family
No. of Seeds 12 No. of Other Members 8
Family Centroid CFAMM00235975 Functional Category Investigative Drug
Superfamily Opioid receptor ligand Tapentadol Superfamily
Class Class 62

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 6 375
Beta adrenergic receptor ligand catecholamine group Isoprotere... 7 130
Opioid receptor ligand opiate Levorphanol Family 18 537
D(1A) dopamine receptor Ligand Fenoldopam Family 4 78
Muscarinic acetylcholine receptor M3 Ligand Tolterodine Family 8 171
Muscarinic acetylcholine receptor M1 Ligand Trihexyphenidyl Fa... 14 199
Kappa-type opioid receptor Ligand Dezocine Family 36 46
Mu-type opioid receptor Ligand Alvimopan Family 32 325
Noradrenergic re-uptake Inhibitor Desvenalfaxine Succinate Family 2 4
Eptazocine Hbr family 6 8
Noradrenergic re-uptake and Opioid receptor Ligand Tapentadol ... 21 79
CORT-108297 family 46 44
5-hydroxytryptamine receptor 1A Ligand (s)-uh-301 Family 35 20
Fibroblast growth factor receptor Ligand SU5403 Family 8 8
Sodium-dependent dopamine transporter and Sodium-dependent nor... 9 16
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 44 3
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 8
D(1A) dopamine receptor ligand (5S)-5-(4-azidophenyl)-8-iodo-3... 2 0
D(1A) dopamine receptor ligand (5R)-8-bromo-3-methyl-5-phenyl-... 6 15
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 1 0
DNA polymerase beta and Thioredoxin glutathione reductase inhi... 1 5


External ID

Functional Category

Molecule Name

CFAMM00235973 DNC013578 Investigative Drug N,N'-(1',7'-heptylene)-bis-(-)-nor-MEP
CFAMM00235985 DNC013577 Investigative Drug N,N'-(1',8'-octylene)-bis-(-)-nor-MEP
CFAMM00235969 DNC013582 Investigative Drug N,N'-(1',4'-butylene)-bis-(-)-nor-MEP
CFAMM00235984 DNC013576 Investigative Drug N,N'-(1',11'-undecydene)-bis-(-)-nor-MEP
CFAMM00235968 DNC013583 Investigative Drug N,N'-(1',3'-propylene)-bis-(-)-nor-MEP
CFAMM00235983 DNC013575 Investigative Drug N,N'-(1',12'-dodecydene)-bis-(-)-nor-MEP
CFAMM00235976 DNC008436 Investigative Drug N,N'-(1',9'-nonylene)-bis-(-)-nor-MEP
CFAMM00235967 DNC013580 Investigative Drug N,N'-(1',5'-pentylene)-bis-(-)-nor-MEP
CFAMM00235982 DNC013574 Investigative Drug N,N'-(1',2'-ethylene)-bis-(-)-nor-MEP
CFAMM00235975 DNC008435 Investigative Drug N,N'-(1',10'-decylene)-bis-(-)-nor-MEP
CFAMM00235981 DNC013579 Investigative Drug N,N'-(1',6-hexylene)-bis-(-)-nor-MEP
CFAMM00235987 DNC004169 Investigative Drug PD-32577

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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