CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1364
Family Name Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-(biphenyl-4-yloxy)-1-oxazol-2-yl-heptan-1-one Family
No. of Seeds 17 No. of Other Members 47
Family Centroid CFAMM00236786 Functional Category Investigative Drug
Superfamily Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-(biphenyl-4-yloxy)-1-oxazol-2-yl-heptan-1-one Superfamily
Class Class 2029

Cousin Family NamesSeedsMembers
Fatty-acid amide hydrolase 1 Inhibitor 1-(oxazol-2-yl)-7-pheny... 12 30
Fatty-acid amide hydrolase 1 Inhibitor 1-(5-(pyridin-2-yl)oxaz... 10 142
Fatty-acid amide hydrolase 1 Inhibitor 2-(7-phenylheptanoyl)ox... 11 4
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-[5-(4-hydroxyphe... 4 36
Fatty-acid amide hydrolase 1 Inhibitor 7-phenyl-1-(5-phenyloxa... 3 3
Fatty-acid amide hydrolase 1 Inhibitor 1-(5-(furan-2-yl)oxazol... 2 1
Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-... 4 15
Histone deacetylase 1 and Histone deacetylase 2 inhibitor 7-[5... 1 2
Fatty-acid amide hydrolase 1 inhibitor SureCN1471727 family 2 19
Fatty-acid amide hydrolase 1 inhibitor methyl 6-[2-[3-(4-pheny... 8 5
Sphingosine 1-phosphate receptor 1 ligand AGN-PC-00DWQL family 2 2
Fatty-acid amide hydrolase 1 inhibitor methyl 5-[2-(7-phenylhe... 2 4
Fatty-acid amide hydrolase 1 inhibitor N-methyl-2-[3-[4-(pheno... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00236831 CHEMBL1765859 Bioactive (5-iodo-1,3-oxazol-2-yl)-[(2S)-6-phenylmethoxy-1,2,3,4-tetrahydronaphthalen-2-yl]methanone
CFAMM00236821 CHEMBL272829 Bioactive 1-(5-iodo-1,3-oxazol-2-yl)-3-[4-(phenoxymethyl)phenyl]propan-1-one
CFAMM00236785 CHEMBL271792 Bioactive 3-(4-phenoxyphenyl)-1-[5-(trifluoromethyl)-1,3-oxazol-2-yl]propan-1-one
CFAMM00236830 CHEMBL1765858 Bioactive AGN-PC-09MANT
CFAMM00236769 CHEMBL486157 Bioactive SureCN4180650
CFAMM00236774 CHEMBL1765834 Bioactive 1,3-oxazol-2-yl-[(2S)-6-phenylmethoxy-1,2,3,4-tetrahydronaphthalen-2-yl]methanone
CFAMM00236773 CHEMBL430036 Bioactive 1-(1,3-oxazol-2-yl)-4-[1-[(3-propan-2-yloxyphenyl)methyl]piperidin-4-yl]butan-1-one
CFAMM00236788 CHEMBL415102 Bioactive 1-(5-iodo-1,3-oxazol-2-yl)-3-(4-phenoxyphenyl)propan-1-one
CFAMM00236795 CHEMBL405604 Bioactive 3-[4-(phenoxymethyl)phenyl]-1-[5-(trifluoromethyl)-1,3-oxazol-2-yl]propan-1-one
CFAMM00236809 CHEMBL1765828 Bioactive 1,3-oxazol-2-yl-[(2S)-6-phenoxy-1,2,3,4-tetrahydronaphthalen-2-yl]methanone
CFAMM00236772 CHEMBL1765836 Bioactive 2-[(2S)-6-phenylmethoxy-1,2,3,4-tetrahydronaphthalene-2-carbonyl]-1,3-oxazole-5-carbonitrile
CFAMM00236787 CHEMBL272038 Bioactive 2-[3-(4-phenoxyphenyl)propanoyl]-1,3-oxazole-5-carbonitrile
CFAMM00236808 CHEMBL1765865 Bioactive 1,3-oxazol-2-yl-[(2S)-5-phenoxy-2,3-dihydro-1H-inden-2-yl]methanone
CFAMM00236834 DNC004273 Investigative Drug 7-(Biphenyl-3-yloxy)-1-oxazol-2-yl-heptan-1-one
CFAMM00236823 DNC013516 Investigative Drug 1-(oxazol-2-yl)-3-(4-phenoxyphenyl)propan-1-one
CFAMM00236839 DNC004276 Investigative Drug 7-(Naphthalen-2-yloxy)-1-oxazol-2-yl-heptan-1-one
CFAMM00236786 DNC004303 Investigative Drug 7-(Biphenyl-4-yloxy)-1-oxazol-2-yl-heptan-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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