CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1383
Family Name Integrin beta-3 Inhibitor Lotrafiban Family
No. of Seeds 5 No. of Other Members 1
Family Centroid CFAMM00237159 Functional Category Investigative Drug
Superfamily Integrin beta-3 Inhibitor Lotrafiban Superfamily
Class Class 1675

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Integrin alpha-4 Inhibitor BIO-1211 Family 16 83
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Integrin beta-3 Inhibitor L-767679 Family 3 6
Integrin beta-3 Inhibitor SKF-107260 Family 5 8
Integrin beta-3 Inhibitor L-750034 Family 7 38
Integrin beta-3 Inhibitor SB-208651 Family 9 28
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Integrin alpha-2 and Integrin beta-3 Inhibitor 3-(3-(carbamoyl... 7 13
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 6 6
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-benz... 5 2
Stromelysin-1 and 72 kDa type IV collagenase inhibitor (2R)-2-... 2 1
Stromelysin-1 inhibitor 6-(4'-FLUORO-BIPHENYL-4-YL)-4-(3-METHY... 3 0
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 5 19
Atrial natriuretic peptide receptor 1 and Atrial natriuretic p... 3 0
Integrin beta-3 and Integrin alpha-IIb inhibitor AGN-PC-009EMK... 2 1
Integrin beta-3 and Integrin alpha-IIb inhibitor AGN-PC-0BOW0P... 1 0
Prothrombin and Coagulation factor X inhibitor AC1NDIV9 family 1 0
NP (s)-methyl 2-(3-(2,5-dioxo-2,3,4,5-tetrahydro-1h-benzo[e][1... 11 3


External ID

Functional Category

Molecule Name

CFAMM00237158 CHEMBL144474 Bioactive AGN-PC-00PFJ1
CFAMM00237155 CHEMBL144681 Bioactive SureCN6705338
CFAMM00237154 CHEMBL143219 Bioactive SureCN6673166
CFAMM00237153 CHEMBL356986 Bioactive SureCN6673128
CFAMM00237159 DNC004308 Investigative Drug LOTRAFIBAN

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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