CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1391
Family Name Farnesyltransferase beta subunit, putative and Protein farnesyltransferase subunit beta Inhibitor L-731735 Family
No. of Seeds 3 No. of Other Members 29
Family Centroid CFAMM00237479 Functional Category Investigative Drug
Superfamily Farnesyltransferase beta subunit, putative and Protein farnesyltransferase subunit beta Inhibitor L-731735 Superfamily
Class Class 1326

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Captopril Family 13 27
Bacterial outer membrane inhibitor polymyxin Colistin Family 26 160
Hepatitis C Vaccine family 1 5
D-alanyl-D-alanine carboxypeptidase Inhibitor Glycyl-l-alpha-a... 5 89
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Alp... 4 18
Sodium/glucose cotransporter 1 Inhibitor Qcpac Family 4 7
Protein farnesyltransferase subunit beta Inhibitor H-smglpcvvm... 2 2
Alpha-galactosidase A Inhibitor AT1001 Family 1 0
Cathepsin L1 and Cathepsin B inhibitor L-Arginine, N2-(N-(N-ac... 1 7
Proprotein convertase subtilisin/kexin type 6 and Furin inhibi... 3 11
Neprilysin inhibitor (2R)-4-methylsulfanyl-2-[2-(sulfanylmethy... 2 1
Neprilysin inhibitor (2R)-3-hydroxy-2-[[10-oxo-9-(sulfanylmeth... 2 1
Angiotensin-converting enzyme 2 and Angiotensin-converting enz... 1 0
4-methylsulfanylbutanoate NP ZINC08790379 Family 25 0
Putative NP ZINC12866068 Family 23 1
NP (s)-2-(1-((s)-2-amino-3-methylbutanoyl)piperidine-4-carboxa... 10 0
4-methylsulfanylbutanoate NP ZINC04084430 Family 18 0


External ID

Functional Category

Molecule Name

CFAMM00237459 CHEMBL2371387 Bioactive (2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2R)-2-amino-3-sulfanylpropyl]amino]-3-methylbutanoyl]amino]-3-methylpentanoyl]amino]-4-methylsulfanylbutanoic acid
CFAMM00237479 DNC004327 Investigative Drug L-731735

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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