CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1396
Family Name Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor Ligand (2,6-dichloro-phenyl)-(1h-imidazol-2-yl)-amine Family
No. of Seeds 5 No. of Other Members 7
Family Centroid CFAMM00237573 Functional Category Investigative Drug
Superfamily Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor Binder Superfamily 3
Class Class 2101

Cousin Family NamesSeedsMembers
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
Benzodiazepine receptor Ligand Midazolam Family 5 160
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
cAMP-specific 3',5'-cyclic phosphodiesterase 4D Inhibitor Arof... 3 196
Kappa-type opioid receptor Ligand Brl 52974 Family 2 27
Histamine H3 receptor and Histamine H4 receptor Ligand Clobenp... 31 38
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Histamine H3 receptor Ligand SCH79687 Family 11 29
Methionine aminopeptidase 2 Inhibitor 2-(pyridin-2-yl)-1h-benz... 6 19
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 1 0
Alpha-1A adrenergic receptor Ligand A-315456 Family 7 17
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-aminobenzyl... 3 6
Adenosine receptor A3 Ligand 2-(5-chloro-1h-benzo[d]imidazol-2... 7 51
Dipeptidyl peptidase 4 Inhibitor (5-phenyl-3h-benzo[d]imidazol... 5 13
Indoleamine 2,3-dioxygenase 1 Inhibitor 3-(4h-imidazol-4-yl)be... 6 3
Aromatase and Cytochrome P450 26A1 Inhibitor Liarozole Family 4 1
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Histamine H3 receptor Ligand 4-(2-(phenylamino)ethyl)-1h-imida... 5 16
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-(2-(4-... 25 10
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 1 7
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 2 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 2 1
Aromatase inhibitor AGN-PC-075MV1 family 1 3
Histamine H3 receptor and Histamine H2 receptor ligand SureCN7... 3 20
D(4) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 2 0
Nociceptin receptor and Potassium voltage-gated channel subfam... 5 2
Histamine H3 receptor ligand AGN-PC-074FK2 family 4 1
Tripeptidyl-peptidase 2 inhibitor (2S)-2-amino-1-[(2S)-5-chlor... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00237574 CHEMBL2206377 Bioactive 3,5-dichloro-N-(1H-imidazol-5-ylmethyl)-N-propan-2-ylaniline
CFAMM00237581 CHEMBL2206385 Bioactive 3-chloro-N-ethyl-N-(1H-imidazol-5-ylmethyl)aniline
CFAMM00237573 DNC004347 Investigative Drug (2,6-Dichloro-phenyl)-(1H-imidazol-2-yl)-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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