CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1406
Family Name Scytalone dehydratase Inhibitor 5-fluoro-2-hydroxy-n-isopropyl-benzamide Family
No. of Seeds 3 No. of Other Members 14
Family Centroid CFAMM00237888 Functional Category Investigative Drug with Natural Product
Superfamily Scytalone dehydratase Inhibitor 5-fluoro-2-hydroxy-n-isopropyl-benzamide Superfamily
Class Class 2105

Cousin Family NamesSeedsMembers
Alpha-1 adrenergic receptor ligand arylethanolamine derivative... 4 37
Muscarinic acetylcholine receptor M3 Ligand Tolterodine Family 8 171
Sodium channel protein type 5 subunit alpha Ligand Flecainide ... 2 162
Mu-type opioid receptor Ligand Alvimopan Family 32 325
Zucapsacin family 7 177
Thymopentin family 20 133
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 6 40
Neuropeptide Y receptor type 1 Ligand Bibp 3226 Family 43 80
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
Dihydroorotate dehydrogenase Inhibitor Salicylhydroxamic Acid ... 2 8
Kynureninase Inhibitor 3-hydroxyhippuric Acid Family 1 9
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 3 89
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Peroxisome proliferator-activated receptor gamma and Peroxisom... 2 4
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 4-hy... 2 13
Histamine H3 receptor Ligand A-349821 Family 49 228
Proto-oncogene tyrosine-protein kinase Src Inhibitor Ac-cys-il... 36 12
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 23 9
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 31 5
Sodium-dependent dopamine transporter and Sodium-dependent nor... 9 16
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Histone deacetylase 1 Inhibitor N-hydroxy-8-(2-methoxyphenyl)-... 2 14
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 49 19
D(2) dopamine receptor Ligand Epidepride Family 31 66
Mu-type opioid receptor Ligand H-tyr-d-ala-aic-asp-val-val-gly... 48 8
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 152 36
Tyrosinase Inhibitor N-(2,4-dihydroxybenzyl)-3,4-dihydroxybenz... 3 2
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 95 46
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 3 10
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 4 2
Angiotensin-converting enzyme and Angiotensin-converting enzym... 3 13
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 6 2
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 2 4
C-C chemokine receptor type 2 ligand 2-amino-N-[2-[[(3R)-1-[(4... 2 6
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 15
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 7 1
Coagulation factor X inhibitor 3-[4-[[(E)-3-[3-(diaminomethyli... 4 6
C-C chemokine receptor type 3 and Probable C-C chemokine recep... 5 2
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 9
Glutamate receptor ionotropic, NMDA 2B ligand AGN-PC-076B5T fa... 1 0
Peptidyl-prolyl cis-trans isomerase A inhibitor N-(9H-fluoren-... 1 1
Benzamides Metabolite Chymosin preparation, escherichia coli k... 1 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00237886 CHEMBL38912 Bioactive BFS
CFAMM00237888 DNC004376 Investigative Drug 5-Fluoro-2-hydroxy-N-isopropyl-benzamide
CFAMM00237878 DNC004385 Investigative Drug 2-Hydroxy-N-(3-phenyl-propyl)-benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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